Emerging patterns of antimicrobial resistance: Concurrent presence of mcr-1.1 and mcr-8.1 in a ST15 Klebsiella pneumoniae isolated from poultry in China

被引：0

作者：

Dongan Cui ^{[1
]}

Panpan Liu ^{[1
]}

Ling Wang ^{[1
]}

Jiongjie He ^{[1
]}

Yuzhang Yan ^{[1
,2
]}

Mengke Ru ^{[1
,2
]}

Baocheng Hao ^{[1
]}

Yan Sun ^{[3
]}

Shengyi Wang ^{[1
]}

机构：

[1] Key Laboratory of New Animal Drug Project, Gansu Province/Key Laboratory of Veterinary Pharmaceutical Development, Ministry of Agriculture and Rural Affairs, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Scienc

[2] College of Animal Science and Technology, Guangxi University

[3] China Institute of Veterinary Drug

来源：

Journal of Integrative Agriculture | 2025年 / 24卷 / 01期

关键词：

D O I：

暂无

中图分类号：

S852.61 [病原细菌];

学科分类号：

摘要：

<正>Highlights ● A ST15 Klebsiella pneumoniae isolate co-harboring mcr-1.1, mcr-8.1 and ESBLs was first detected in laying hens. ● The pNXQY01-5 harbored the bla CTX-M-55 and mcr-1.1 genes linked to insertion sequences ISEc9 and ISApl1.● The pNXQY01-2, pNXQY01-3, and pNXQY01-5 facilitated the horizontal transfer of resistance genes mcr-8.1, bla CTX-M-65, mcr-1.1 and bla CTX-M-55.Colistin serves as a crucial treatment for multidrugresistant(MDR) Gram-negative bacterial infections. However, its excessive use has contributed to an increase in colistin-resistant strains within livestock production(Binsker et al. 2022).

引用

页码：403 / 407

页数：5

共 8 条

[1] Emerging patterns of antimicrobial resistance: Concurrent presence of mcr-1.1 and mcr-8.1 in a ST15 Klebsiella pneumoniae isolated from poultry in China
Cui, Dong'an
Liu, Panpan
Wang, Ling
He, Jiongjie
Yan, Yuzhang
Ru, Mengke
Hao, Baocheng
Sun, Yan
Wang, Shengyi
JOURNAL OF INTEGRATIVE AGRICULTURE, 2025, 24 (01) : 403 - 407
[2] First report of plasmid-mediated colistin resistance mcr-8.1 gene from a clinical Klebsiella pneumoniae isolate from Lebanon
Salloum, Tamara
Panossian, Balig
Bitar, Ibrahim
Hrabak, Jaroslav
Araj, George F.
Tokajian, Sima
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL, 2020, 9 (01)
[3] First report of plasmid-mediated colistin resistance mcr-8.1 gene from a clinical Klebsiella pneumoniae isolate from Lebanon
Tamara Salloum
Balig Panossian
Ibrahim Bitar
Jaroslav Hrabak
George F. Araj
Sima Tokajian
Antimicrobial Resistance & Infection Control, 9
[4] Emergence of high-level colistin resistance mediated by multiple determinants, including mcr-1.1, mcr-8.2 and crrB mutations, combined with tigecycline resistance in an ST656 Klebsiella pneumoniae
Wang, Yanfei
Zhou, Junxin
Liu, Haiyang
Wang, Qian
Zhang, Ping
Zhu, Jingyi
Zhao, Dongdong
Wu, Xueqing
Yu, Yunsong
Jiang, Yan
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2023, 13
[5] Draft genome sequence analysis of a mcr-1-producing Klebsiella pneumoniae ST661 isolated from a mink in China
Sun, Na
Luo, Yilin
Zhao, Yaru
Wang, Guisheng
Guo, Li
Liu, Liming
San, Zhihao
Zhao, Cuiqing
Cheng, Yuening
Chen, Qiang
JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE, 2024, 37 : 72 - 74
[6] Plasmid-mediated colistin resistance gene mcr-1 in Escherichia coli and Klebsiella pneumoniae isolated from market retail fruits in Guangzhou, China
Yang, Fan
Shen, Cong
Zheng, Xiaobin
Liu, Yan
Ahmed, Mohamed Abd El-Gawad El-Sayed
Zhao, Zihan
Liao, Kang
Shi, Yaling
Guo, Xin
Zhong, Ruoxuan
Xu, Zhimin
Tian, Guo-Bao
INFECTION AND DRUG RESISTANCE, 2019, 12 : 385 - 389
[7] The prevalence of colistin resistance in Escherichia coli and Klebsiella pneumoniae isolated from food animals in China: coexistence of mcr-1 and blaNDM with low fitness cost
Wang, Ruobing
Liu, Yuqing
Zhang, Qing
Jin, Longyang
Wang, Qi
Zhang, Yawei
Wang, Xiaojuan
Hu, Ming
Li, Lulu
Qi, Jing
Luo, Yanbo
Wang, Hui
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 2018, 51 (05) : 739 - 744
[8] Convergence of MCR-8.2 and Chromosome-Mediated Resistance to Colistin and Tigecycline in an NDM-5-Producing ST656 Klebsiella pneumoniae Isolate From a Lung Transplant Patient in China
Zhao, Jiankang
Li, Ziyao
Zhang, Yulin
Liu, Xinmeng
Lu, Binghuai
Cao, Bin
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 12

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