Pd(<sc>ii</sc>)-catalyzed B(9)-alkynylation of o/m-carboranes

被引：1
|
作者：
Zhang, Hao-Tian [1 ]
Gao, Yan [2 ]
Ma, Yan-Na [1 ]
Chen, Xuenian [1 ,2 ]
机构：
[1] Zhengzhou Univ, Coll Chem, Zhengzhou 450001, Henan, Peoples R China
[2] Henan Normal Univ, Sch Chem & Chem Engn, Henan Key Lab Boron Chem & Adv Energy Mat, Xinxiang 453007, Henan, Peoples R China
来源：
ORGANIC CHEMISTRY FRONTIERS | 2024年 / 11卷 / 23期
基金：
中国国家自然科学基金;
关键词：
O-CARBORANES; CLICK CHEMISTRY;
D O I：
10.1039/d4qo01428f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Alkyne motifs are important building blocks in organic syntheses. Therefore, introducing alkynyl groups into molecules is highly desirable. Herein, we developed a Pd(II)-catalyzed selective B(9)-alkynylation of o-carboranes and m-carboranes with (Pr3SiCCBr)-Pr-i as the alkynylated reagent. Ratios of 6 : 1 for o-carboranes and >20 : 1 for m-carboranes were detected in this reaction. Desilylation of the resultant product affords carboranyl acetylene, which can undergo further transformation to provide a diverse range of functional carboranes.
引用
收藏
页码：6706 / 6711
页数：6
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