Research Progress in the Design of Rare-earth Up-conversion Luminescent Materials and Their Application in Photodynamic Therapy

被引：0
|
作者：
Gan X. [1 ]
Su Y. [1 ]
Ying W. [2 ]
Wang J. [2 ]
Liu L. [1 ]
Zhou X. [2 ]
Wen S. [1 ]
机构：
[1] Beijing Engineering Research Center of Advanced Elastomers, Beijing University of Chemical Technology, Beijing
[2] Department of Urology, China-Japan Friendship Hospital, Beijing
来源：
Cailiao Daobao/Materials Reports | 2024年 / 38卷 / 08期
关键词：
cancer therapy; photodynamics therapy; photosensitizers; rare-earth up-conversion luminescent material;
D O I：
10.11896/cldb.22080243
中图分类号：
学科分类号：
摘要：
As an emerging non-invasive therapeutic approach, photodynamic therapy is an ideal cancer treatment method due to the low number of side effects, low cumulative toxicity, effective tumor destruction, and precise targeting without damaging adjacentA tissues. In this review, we first briefly outline the mechanism, basic elements, and cellular reaction mechanisms of photodynamic therapy. After that, the design features of rare-earth up-conversion luminescent materials and the requirements of photodynamic therapy for up-conversion luminescent materials are discussed. In addition, the material combination methods of up-conversion luminescent nanomaterials, photosensitizers, and targeting substances, as well as the application effects, are summarized. Lastly, the progress of synergistic therapy combining photodynamic therapy with radiotherapy, chemotherapy, and photothermal therapy is reviewed. © 2024 Cailiao Daobaoshe/ Materials Review. All rights reserved.
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