Roles and fates of antibiotics in anaerobic digestion of waste activated sludge: Insights to pro- and re-duction of antibiotic resistance genes

被引：0

作者：

Meng, Qing-Bin ^{[1
,2
]}

He, Zhang-Wei ^{[1
,2
]}

Yang, Wenjing ^{[3
]}

Li, Wen-Tao ^{[4
]}

Tang, Cong-Cong ^{[1
,2
]}

Zhou, Ai-Juan ^{[5
]}

Ren, Yong-Xiang ^{[1
,2
]}

Liu, Wenzong ^{[6
,7
]}

Li, Zhihua ^{[1
,2
]}

Wang, Aijie ^{[6
,7
]}

机构：

[1] Key Laboratory of Northwest Water Resource, Environment and Ecology, Ministry of Education, School of Environmental and Municipal Engineering, Xi'an University of Architecture and Technology, Xi'an,710055, China

[2] Shaanxi Key Laboratory of Environmental Engineering, Xi'an University of Architecture and Technology, Xi'an,710055, China

[3] Central & Southern China Municipal Engineering Design and Research Institute Co., Ltd., Wuhan,430010, China

[4] PowerChina Northwest Engineering Corporation Limited, Xi'an,710065, China

[5] College of Environmental Science and Engineering, Taiyuan University of Technology, Taiyuan,030024, China

[6] State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin,150090, China

[7] State Key Laboratory of Urban Water Resource and Environment, School of Civil and Environmental Engineering, Harbin Institute of Technology Shenzhen, Shenzhen,518055, China

来源：

Chemical Engineering Journal | 2024年 / 500卷

基金：

中国国家自然科学基金;

关键词：

Anaerobic digestion (AD) of waste activated sludge (WAS) is considered as a promising alternative to realize sludge stabilization and bioenergy recovery; thereby driving carbon neutrality in wastewater treatment plants. However; most of antibiotics are adsorbed by sludge flocs rather than bio-degraded in wastewater treatment process. Regarding that the accumulation of antibiotics in WAS can not only affect performance of AD but also induce the production of antibiotic resistance genes (ARGs); presenting great ecological risks; this review systematically highlighted the recent progress on the fates and roles of antibiotics in AD of WAS; the production and spread of ARGs related to antibiotics and co-contaminants; and the reduction and control strategies of antibiotics and ARGs. The effects of antibiotics on AD stages like solubilization; hydrolysis; acidogenesis; and methanogenesis are type- and dose-dependent. The co-existence of antibiotics and other contaminants enhances the spread of ARGs via enriching potential antibiotic resistance bacteria and promoting horizontal gene transfer; and the control of intracellular ARGs is the key to improve ARGs removal in AD. To mitigate the ecological risks posed by antibiotics and ARGs; the enhanced strategies like pretreatment; conductive materials; anaerobic co-digestion; and microbial electrolysis cell-assisted anaerobic digestion have been explored. In the future study; the interaction mechanisms between the transfer of ARGs and key metabolic genes in microorganisms responded to co-pollutants should be verified to reveal the potential relationships among co-pollutants; ARGs transfer; and bacterial metabolism. After that; the green and economical strategies for simultaneous resource recovery and pollutants removal enhancement should be explored. Moreover; machine learning technique are urgently needed to quantitatively assess the ecological and human health risks caused by residual antibiotics and ARGs. © 2024 Elsevier B.V;

D O I：

10.1016/j.cej.2024.156633

中图分类号：

学科分类号：

摘要：

引用

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