The Design of Scanning Laser Optical Tomography Imaging System and Its Applications

被引：0
|
作者：
Xue C.-Z. [1 ,2 ,4 ]
Li Y.-M. [1 ,2 ,5 ]
Li G.-Y. [1 ,2 ,3 ]
Li Y.-C. [1 ,2 ,3 ]
Hu X.-J. [1 ,2 ,3 ]
Chen L.-L. [1 ,2 ,3 ]
机构：
[1] Shenzhen Key Laboratory of Laser Engineering, Shenzhen, 518060, Guangdong
[2] Key Laboratory of Advanced Optical Precision Manufacturing Technology of Guangdong Higher Education Institutes, Shenzhen University, Shenzhen, 518060, Guangdong
[3] College of Optoelectronic Engineering, Shenzhen University, Shenzhen, 518060, Guangdong
[4] College of Electronic Science and Technology, Shenzhen University, Shenzhen, 518060, Guangdong
[5] College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, 518060, Guangdong
来源：
Chen, Ling-Ling (l.chen10@szu.edu.cn) | 1600年 / Chinese Optical Society卷 / 46期
基金：
中国国家自然科学基金;
关键词：
Biological organs; Fluorescence microscopy; Imaging systems; LabVIEW; Mesoscopic size; Scanning laser optical tomography; Three-dimensional information;
D O I：
10.3788/gzxb20174607.0722003
中图分类号：
学科分类号：
摘要：
This paper presented a self-designed scanning laser optical tomography mesoscopic imaging system based on LabVIEW and explored its capabilities to image intact biological organs or tissues. The system is consisted of an aligned laser, a four dimension translation stage, a scanning mirror and a photomultiplier tube. The spatial resolution of the system is better than 20 μm with an imaging field of 1 cm. The system operation process and preliminary biomedical applications were demonstrated through the 3-D autofluorescence imaging of a mouse lung. Compared to the traditional biomedical optical imaging techniques, scanning laser optical tomography provides the advantages of high photon collection efficiency, large sample range and easy operation. © 2017, Science Press. All right reserved.
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