Efficient synthesis of optically active 2,3-allenols via the simple CuBr-mediated reaction of optically active propargylic alcohols with paraformaldehyde

被引：0
|
作者：
Ma, Shengming [1 ]
Hou, Hairong [1 ]
Zhao, Shimin [1 ]
Wang, Guangwei [1 ]
机构：
[1] State Key Lab. Organometallic Chem., Shanghai Inst. of Organic Chemistry, Chinese Academy of Sciences, 354 Fenglin Lu, Shanghai 200032, China
来源：
Synthesis | 2002年 / 12期
关键词：
Formaldehyde; -; Synthesis; (chemical);
D O I：
10.1055/s-2002-33656
中图分类号：
学科分类号：
摘要：
Enantiomerically enriched 2,3-allenols were prepared by the CuBr-mediated homologation of the relatively easily available optically active terminal propargylic alcohols with paraformaldehyde in the presence of diisopropylamine.
引用
收藏
页码：1643 / 1645
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