Prediction of pharmacokinetic behaviour by combining in vivo and in vitro data in physiologically based pharmacokinetic (PBPK) model: Parameter estimation and sensitivity analysis

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Das, Debasish [1 ]
Dhurjati, Prasad [2 ]
Wangikar, Pramod P. [1 ,3 ]
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[1] Department of Chemical Engineering, Indian Institute of Technology, Bombay, Powai, Mumbai 400076, India
[2] Department of Chemical Engineering, University of Delaware, Newark, DE 19716, United States
[3] School of Biosciences and Bioengineering, Indian Institute of Technology, Bombay, Powai, Mumbai 400076, India
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页码:57 / 71
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