Conjugation of haloperidol to PEG allows peripheral localisation of haloperidol and eliminates CNS extrapyramidal effects

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作者：
Natfji, Az Alddien [1 ]
Nikitin, Dmitry O. [2 ]
Semina, Irina I. [2 ]
Moustafine, Rouslan I. [3 ]
Khutoryanskiy, Vitaliy V. [1 ,3 ]
Lin, Hong [1 ]
Stephens, Gary J. [1 ]
Watson, Kimberly A. [4 ]
Osborn, Helen M.I. [1 ]
Greco, Francesca [1 ]
机构：
[1] Reading School of Pharmacy, University of Reading, Whiteknights, Reading,RG6 6AD, United Kingdom
[2] Department of Pharmacology, Kazan State Medical University, 6/30 Tolstogo Street, Kazan,420012, Russia
[3] Institute of Pharmacy, Kazan State Medical University, 16 Fatykh Amirkhan Street, Kazan,420126, Russia
[4] Institute of Cardiovascular and Metabolic Research, School of Biological Sciences, University of Reading, Whiteknights, Berkshire,RG6 6AS, United Kingdom
来源：
Journal of Controlled Release | 2020年 / 322卷
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页码：227 / 235
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