Molecular mechanisms on sensitization and immune regulation of major allergens from crustaceans

The growing international trade in crustacean seafood products has enhanced the popularity and frequency of consumption across many countries. The increased production and consumption of crustacean seafood has been accompanied by more frequent reports of adverse health problems especially referred to allergy. In this review, the structure and identification methods of different allergic proteins in crustaceans are introduced. Moreover, the molecular mechanisms on allergic response and immune regulation of major allergens from crustaceans are mainly elucidated.