New synthetic method for the N-acetylation of cysteine

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作者：
Xu, Heng
Zhang, Qun
Kong, Xue-jun
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Jingxi Huagong/Fine Chemicals | 2000年 / 17卷 / 04期
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摘要：
A new synthetic method for acetylation of cysteine using acetic anhydride as acetylation agent was described and the optimum conditions for the reaction were obtained. Molar ratio of acetic anhydride and cysteine was 1.30:1.25. The acetylation agent was added in twice. The reaction temperature was controlled in 3 stages: 10-12, 35-38, 55-60 °C. The recrystallization agent was ethyl alcohol. The yield was 83.1% and the purity of product is 99.3%.
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页码：205 / 207
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