Effects of extremely low frequency electromagnetic fields on the hematopoietic system of the SD Rats

被引：0
|
作者：
Zhang Y. [1 ]
Lai J. [2 ]
Zhang J. [1 ]
Zhao J. [1 ]
Wan H. [1 ]
Chen C. [2 ]
机构：
[1] State Key Laboratory of Power Grid Environmental Protection, China Electric Power Research Institute, Wuhan
[2] Department of Cardiology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan
来源：
Chen, Chen (chenchen@tjh.tjmu.edu.cn) | 2016年 / Science Press卷 / 42期
关键词：
Blood routine examination; Bone marrow biopsy; Cytology; Extremely low frequency electromagnetic fields; Hematopoietic system; SD rats;
D O I：
10.13336/j.1003-6520.hve.20160812010
中图分类号：
学科分类号：
摘要：
In order to study the effects of extremely-low-frequency electromagnetic fields (ELF-EMFs) on the hematopoietic system of SD rats. 128 SD rats were divided into 2 groups, the exposure group and the control group. The SD rats in the exposure group were subjected to an ELF-EMFs with a magnetic induction intensity of 100 μT and a frequency of 50 Hz for 12 weeks, 20 hours per day; while the SD rats in the control group were put to a similar device without ELF-EMFs. The peripheral blood hematogram was carried out for all the rats before the exposure and after 12 weeks of exposure. Moreover, the femur and spleen of the SD rats were collected and subjected to haematoxylin-eosin (HE) staining at the end of the exposure period, and their structures were observed. Further, the bone marrow biopsy of the SD rats were analyzed in cytology, and the cell types in spleen of the SD rats were detected. The results show that, compared with the SD rats in the control group, the SD rats in the exposure group have no difference in the white blood cell count, the ratio of neutrophil and the ratio of lymphocyte. Meanwhile, results of the red blood cell count, hemoglobin concentration and platelet count show no significant difference between the two groups. The HE staining results show that the structures of the bone marrow and spleen for the SD rats are not affected by the ELF-EMFs exposure. Moreover, the bone marrow biopsy analyses show that the ELF-EMFs exposure have not led to abnormal cytology of the SD rats bone marrows, and there are no differences in spleen cell types between the rats in exposure group and control group. The results above prove that the ELF-EMFs with a magnetic induction intensity of 100 μT and a frequency of 50 Hz have no effects on the hematopoietic system of the SD rats. © 2016, High Voltage Engineering Editorial Department of CEPRI. All right reserved.
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页码：2435 / 2443
页数：8
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