Capability of energetic metabolism of cell to activate a reparation of the cellular genetic material after radiation damages

被引：0

作者：

Kozyreva, E.V. ^{[1
]}

Eliseenko, N.N. ^{[1
]}

机构：

[1] Inst. Gen. Path. Pathophys., Russian Acad. of Medical Sci., Baltijskaya ul. 8, Moscow, 125315, Russia

来源：

Radiatsionnaya Biologiya. Radioekologiya | 2002年 / 42卷 / 06期

关键词：

Adenosinetriphosphate - Cells - Growth kinetics - Metabolism - Neutrons - Radiation protection;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

A new hypothesis on a mechanism of action of the radioprotective and medical preparations involving the activation of oxidative phosphorylation and biogenesis of mitochondria which provides the increase of dimension and rapidity of the cellular reparation has been suggested. A previously unknown property of mitochondrions to determine a cellular homeostasis has been found. An activation of oxidative phosphorylation of mitochondria is a way of cellular protection against extreme conditions (namely, against radiation exposure and tumor formation).

引用

页码：632 / 635

共 31 条

[1] Malate-Based Biodegradable Scaffolds Activate Cellular Energetic Metabolism for Accelerated Wound Healing
Wu, Min
Zhao, Yitao
Tao, Meihan
Fu, Meimei
Wang, Yue
Liu, Qi
Lu, Zhihui
Guo, Jinshan
ACS APPLIED MATERIALS & INTERFACES, 2023, 15 (44) : 50836 - 50853
[2] REPARATION OF ENERGY-METABOLISM OF ASSIMILATING CELL AFTER EFFECT OF EXTREMAL TEMPERATURE
PETROV, VE
LOSKUTNIKOV, AI
FIZIOLOGIYA I BIOKHIMIYA KULTURNYKH RASTENII, 1977, 9 (02): : 202 - 209
[3] ROLE OF LIGHT IN REPARATION OF ENERGY-METABOLISM OF ASSIMILATING CELL AFTER HEAT AFFECTION
LOSKUTNIKOV, AI
PETROV, VE
FIZIOLOGIYA I BIOKHIMIYA KULTURNYKH RASTENII, 1978, 10 (02): : 204 - 210
[4] ORIGIN AND REPAIR OF RADIATION-DAMAGE OF THE GENETIC MATERIAL IN A CELL
不详
CHEMIKER-ZEITUNG, 1981, 105 (7-8): : 219 - 222
[5] Consequences of Mixotrophy on Cell Energetic Metabolism in Microchloropsis gaditana Revealed by Genetic Engineering and Metabolic Approaches
Bo, Davide Dal
Magneschi, Leonardo
Bedhomme, Mariette
Billey, Elodie
Deragon, Etienne
Storti, Mattia
Menneteau, Mathilde
Richard, Christelle
Rak, Camille
Lapeyre, Morgane
Lembrouk, Mehdi
Conte, Melissa
Gros, Valerie
Tourcier, Guillaume
Giustini, Cecile
Falconet, Denis
Curien, Gilles
Allorent, Guillaume
Petroutsos, Dimitris
Laeuffer, Frederic
Fourage, Laurent
Jouhet, Juliette
Marechal, Eric
Finazzi, Giovanni
Collin, Severine
FRONTIERS IN PLANT SCIENCE, 2021, 12
[6] Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA
Yang, Xuan
Wang, Haomiao
Huang, Chuchu
He, Xiaoyun
Xu, Wentao
Luo, Yunbo
Huang, Kunlun
SCIENTIFIC REPORTS, 2017, 7
[7] Zinc enhances the cellular energy supply to improve cell motility and restore impaired energetic metabolism in a toxic environment induced by OTA
Xuan Yang
Haomiao Wang
Chuchu Huang
Xiaoyun He
Wentao Xu
Yunbo Luo
Kunlun Huang
Scientific Reports, 7
[8] Genetic architecture of the acute and persistent immune cell response after radiation exposure
He, Li
Zhong, Chenhan
Chang, Hang
Inman, Jamie L.
Celniker, Susan E.
Ioakeim-Ioannidou, Myrsini
Liu, Kevin X.
Haas-Kogan, Daphne
Macdonald, Shannon M.
Threadgill, David W.
Kogan, Scott C.
Mao, Jian-Hua
Snijders, Antoine M.
CELL GENOMICS, 2023, 3 (11):
[9] Recombinant forms of the neurotrophic factor pigment epithelium-derived factor activate cellular metabolism and inhibit proliferation of the RAW macrophage cell line
Cohen, J
Sugita, Y
Chader, GJ
Schwartz, JP
NEUROIMMUNOMODULATION, 2000, 7 (01) : 51 - 58
[10] Cellular responses of osteoblastic and osteocyte-like cell lines after exposure to ionizing radiation
Lau, P.
Hellweg, C. E.
Hu, Y.
Baumstark-Khan, C.
Reitz, G.
BONE, 2011, 48 : S139 - S139

← 1 2 3 4 →