Preparation and Characterization of Poly(lactic acid) Microcapsules by Layer-by-Layer Self-Assembly Method

被引：0
|
作者：
Li Y. [1 ]
Wang M. [1 ]
Zhang H. [1 ]
Yang G. [1 ]
Shao H. [1 ]
机构：
[1] State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, College of Material Science and Engineering, Donghua University, Shanghai
来源：
Yang, Gesheng (gsyang@dhu.edu.cn) | 1600年 / Sichuan University卷 / 33期
关键词：
Layer-by-layer self-assembly; Microcapsules; Poly(lacticacid); Stereocomplex;
D O I：
10.16865/j.cnki.1000-7555.2017.08.028
中图分类号：
学科分类号：
摘要：
Poly(lacticacid)(PLA) microcapsules were fabricated by layer-by-layer self-assembly of poly(L-lactic acid)(PLLA) and poly(D-lactic acid)(PDLA) onto the CaCO3 templates which were synthesized from Na2CO3 and CaCl2, followed by removing CaCO3 templates using ethylene diamine tetraacetic acid (EDTA). The microcapsules were characterized by SEM, AFM, TEM, CLSM, DSC, and XRD. The results show that the interlayer driving force of microcapsules is the stereocomplex affection between PLA isomers. The morphology of microcapsule displays classical drape. The thickness of microcapsule wall is between 90nm and 100 nm, and the small molecules can pass through the wall. Therefore, the prepared capsules have potential application in the field of drug sustained releasing. © 2017, Editorial Board of Polymer Materials Science & Engineering. All right reserved.
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页码：158 / 162
页数：4
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