A rigid model wind tunnel test was carried out for thin spherical shell roof structure. The variation rule and the calculation method of the average shape coefficient of the average pulsating wind pressure under the six typical wind angles were obtained. Fluctuating wind pressure on coefficient change rule and the calculation method of shape coefficient under six kinds of typical wind direction angle, and the structural analysis of the node deflection and cross section stress of MIDAS/GEN software was analyzed in the wind pressure field. Through the quantitative analysis of the change rule between the mechanics-flow form of the typical spherical shell and the wind pressure distribution, calculating results were in comparison with wind tunnel test data. The research results show that the wind vibration research and analysis of the mechanical characteristics of structural mechanics in different working conditions provide a reliable theoretical basis for the mechanical index of the wind vibration. © 2018, Editorial Board of Journal of Huazhong University of Science and Technology. All right reserved.