Chitosan-manuka honey composite wound dressings

This study is focused on the development of bioactive composite wound dressings with desirable wound healing properties using needlepunched nonwovens, chitosan, and manuka honey. 3 different methods using film, halftone, and dip and dry techniques, were devised to prepare chitosan-honey wound dressings with viscose and bamboo nonwovens as secondary layer and chitosan-manuka honey as primary layer. All dressings prepared were evaluated for their effectiveness as wound dressing and characterized. The results indicate that the weight and thickness of almost all the samples are comparable. The film dressings showed a higher value of air permeability and water vapor transmission of 55 cm3/cm2/s and 1,700 g/m2/day.The swelling ratio of film dressings was 283%. Even though dip and dry dressings showed better antimicrobial activity and higher tensile strength, their elongation is low compared to film dressings. Halftone treated samples show poor coating in the morphological observation. Hence, from the obtained results, it can be concluded that the film wound dressings show considerable advantage over halftone and dip and dry dressings. © 2018 Deutscher Fachverlag GmbH. All Rights Reserved.