Fabrication of pH Responsive Chitosan-Furfural Hydrogel and Its Self-Healing Ability

被引：0

作者：

Dong C. ^{[1
]}

Wang H. ^{[1
]}

Liu C. ^{[1
]}

Zhang Z. ^{[1
]}

Yang Y. ^{[1
]}

机构：

[1] College of Chemistry and Chemical Engineering, Cangzhou Normal University, Cangzhou

来源：

Liu, Changxia (lcx822@sohu.com) | 1600年 / Sichuan University卷 / 36期

关键词：

Chitosan; Furfural; Hydrogel; PH responsiveness; Self-healing;

D O I：

10.16865/j.cnki.1000-7555.2020.0253

中图分类号：

学科分类号：

摘要：

The chitosan hydrogels (CS-F) were prepared by the natural products, chitosan and furfural. The hydrogel structure was characterized by FT-IR and XRD, and its pH responsiveness, swelling behavior, rheological property and self-healing ability were discussed in detail. The experimental results show that furfural was successfully grafted onto the chitosan molecular chains through imine bonds and 3D cross-linked networks were formed by the order arrangement of supramolecular layers. The CS-F-0.7 hydrogel for n(-NH2): n(-CHO)=1: 0.7 shows the pH responsiveness for gel-sol phase transition, swelling behavior and self-healing ability due to the dynamic imine and free amino groups of chitosan chain. The CS-F-1.0 hydrogel for n(-NH2): n(-CHO)=1: 1 loses its swelling behavior and self-healing ability. In the acid medium, the CS-F-0.7 xerogel shows the instant self-healing ability. The CS-F hydrogels constructed with two biological materials show the good self-healing ability and pH responsiveness, and have broad application prospects in the fields of drug delivery and tissue engineering. © 2020, Editorial Board of Polymer Materials Science & Engineering. All right reserved.

引用

页码：127 / 133and138

共 15 条

[1] Li J, Zhao Z N, Li Z Z, Et al., Synthetic mechanism and biomedical application of self-healing hydrogel, Materials Reports, 33, 10, pp. 3328-3335, (2019)
[2] Ding F Y, Li H B, Du Y M, Et al., Recent advances in chitosan-based self-healing materials, Research on Chemical Intermediates, 44, pp. 4827-4840, (2018)
[3] Chen L M, Wang T, Li K., Preparation of chitosan/hydroxypropyl methyl cellulose thermo-sensitive hydrogel, Polymer Materials Science & Engineering, 32, 11, pp. 156-161, (2016)
[4] Iftime M M, Morariu S, Marin L., Salicyl-imine-chitosan hydrogels: supramolecular architecturing as a crosslinking method toward multifunctional hydrogels, Carbohydrate Polymers, 165, pp. 39-50, (2017)
[5] Xu C H, Zhan W, Tang X Z, Et al., Self-healing chitosan/vanillin hydrogels based on Schiff-base bond/hydrogen bond hybrid linkages, Polymer Testing, 66, pp. 155-163, (2018)
[6] Xu Y S, Li Y S, Chen Q M, Et al., Injectable and self-healing chitosan hydrogel based on imine bonds: design and therapeutic applications, International Journal of Molecular Sciences, 19, (2018)
[7] Li X F, Feng X Q, Ma G J., Synthesis and interaction with DNA of schiff base constructed from furfural and nicotinic hydrazide, Journal of Materials Science & Engineering, 37, 4, pp. 641-644, (2019)
[8] He G H, Zhao S, Wang H B, Et al., Preparation and properties of carboxyethyl chitosan/polyvinyl alcohol self-healing hydrogel, Journal of Wuhan University(Natural Science Edition), 65, 4, pp. 369-376, (2019)
[9] Deng H J, Ye Y J, Wang W J, Et al., Enhancing mechanical performance and intelligent response of chitosan/mahPEGmah-N-vinylpyrrolide double network hydrogel, Polymer Materials Science & Engineering, 31, 2, pp. 81-87, (2015)
[10] Jia T J, Li P W, Shang Z G, Et al., The study on raman and infrared spectra of furfural molecule, Chinese Journal of Light Scattering, 19, 1, pp. 1-5, (2007)

← 1 2 →