Synthesis of fluorinated 2-phenyl-4-quinolones from pyrrole-2,3-diones

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作者
Ramana Rao, V.V. [1 ]
Wentrup, Curt [1 ]
机构
[1] Department of Chemistry, The University of Queensland, Brisbane, QLD 4072, Australia
关键词
Molecular structure - Substitution reactions - Synthesis (chemical) - Thermoanalysis;
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摘要
A series of substituted 2-phenyl-4-quinolones 8-11 have been synthesized in good yields via flash vacuum thermolysis (FVT) of 1-aryl-4-cyano-5-phenylpyrrole-2,3-diones 7a-e and 1-aryl-4-methoxycarbonyl-5-phenylpyrrole-2,3-diones 7f-j. The pyrrolediones 7 were prepared from amines 3 and benzoylacetonitriles 5a-e or methyl 3-arylamino-3-phenylprop-2-enoates 5f-j.
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页码:1232 / 1235
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