In this work, the cutting performance of wood-plastic composite was in focus. To this end, a series of milling experiments were carried out to study the effects of tool rake angle, spindle speed and cutting depth on the cutting forces and surface roughness via orthogonal experimental design. The results obtained are as follows: firstly, the cutting force is negatively related with the increase of rake angle and spindle speed, but has a positive correlation with the increased cutting depth. Then, the surface roughness increases with decreased rake angle and increased cutting depth. However, as spindle speed continuously increases, the surface roughness first declines and then increases. Thirdly, the prominence order of the factors affecting both cutting forces and surface roughness is cutting depth, followed by rake angle and spindle speed. Finally, based on verifying test, the optimum cutting parameters when milling wood-plastic composite with diamond cutters are 15° front angle, 6000r/min spindle speed, 0.5mm cutting depth. © 2020, Cefin Publishing House. All rights reserved.