How to make biology more "engineering"

被引：0
|
作者：
Xiao W. [1 ,2 ]
Zhou S. [1 ,2 ]
Wang Y. [1 ,2 ]
Yuan Y. [1 ,2 ]
机构：
[1] Key Laboratory of Systems Bioengineering(Ministry of Education), Tianjin University, Tianjin
[2] SynBio Research Platform, Collaborative Innovation Center of Chemical Science and Engineering(Tianjin), Tianjin
来源：
Yuan, Yingjin (yjyuan@tju.edu.cn) | 1827年 / Materials China卷 / 35期
关键词：
design-bulid-test" cycle; Compatibility; Modularization; Orthogonality; Robustness; Synthetic biology;
D O I：
10.16085/j.issn.1000-6613.2016.06.024
中图分类号：
学科分类号：
摘要：
With the development and application of chemistry, chemical engineering arises at the historic moment. Similarly, with the development of biology and engineering requirement, synthetic biology, known as "the third revolutions of biology", was born. Synthetic biology is the engineering of biology. From the point of view of engineering, it designs and creates parts, devices or modules, and employs them to modify and optimization of existing natural biological system, but how to engineer complex life system is the key scientific problem which synthetic biology researchers have long been exploring. In this paper, the main four characteristics of engineering biology are systematically illustrated: (1)modularization and standardization; (2)orthogonality; (3)robustness; (4)compatibility, as well as the corresponding research progress. Finally, from the point of view of "Design-Build -Test" cycle, proposals for how to further engineer biology in the future are addressed. © 2016, Chemical Industry Press. All right reserved.
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页码：1827 / 1836
页数：9
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