Exploring kinase family inhibitors and their moiety preferences using deep SHapley additive exPlanations

被引：0
|
作者：
Fan, You-Wei [1 ]
Liu, Wan-Hsin [2 ,3 ,4 ]
Chen, Yun-Ti [2 ]
Hsu, Yen-Chao [2 ]
Pathak, Nikhil [5 ]
Huang, Yu-Wei [6 ]
Yang, Jinn-Moon [2 ,7 ]
机构：
[1] Institute of Molecular Medicine and Bioengineering, National Chiao Tung University, Hsinchu,30050, Taiwan
[2] Institute of Bioinformatics and Systems Biology, National Chiao Tung University, Hsinchu,30050, Taiwan
[3] Institute of Information Science, Academia Sinica, Taipei,11564, Taiwan
[4] Bioinformatics Program, Taiwan International Graduate Program, Academia Sinica, Taipei,11564, Taiwan
[5] Institute of Bioinformatics and Structural Biology, National Tsing Hua University, Hsinchu,30044, Taiwan
[6] Institute of Biomedical Engineering, National Chiao Tung University, Hsinchu,30050, Taiwan
[7] Department of Biological Science and Technology, National Chiao Tung University, Hsinchu,30050, Taiwan
来源：
BMC Bioinformatics | 2022年 / 23卷
关键词：
Compendex;
D O I：
242
中图分类号：
学科分类号：
摘要：
Deep neural networks - Diseases - Enzyme inhibition - Signal transduction
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