Research Progress in the Regulation Mechanisms of White and Brown Adipose Tissue in the Body by Functionally Active Factors

被引：0
|
作者：
Tan T. [1 ]
Luo Y. [1 ]
Sun W. [1 ]
机构：
[1] College of Agriculture and Animal Husbandry, Qinghai University, Xining
来源：
Shipin Kexue/Food Science | 2023年 / 44卷 / 15期
关键词：
active factors; brown adipose tissue; physical health; thermogenesis-related genes;
D O I：
10.7506/spkx1002-6630-20230220-186
中图分类号：
学科分类号：
摘要：
Brown adipose tissue (BAT) improves the metabolic level of the body by promoting energy expenditure, which can contribute to the prevention and treatment of metabolic diseases such as obesity and diabetes, and BAT has become a new target for the treatment of metabolic diseases. BAT activity enhancement in the body is a hot topic but also a challenge for researchers, and research and analysis of functionally active factors in foods that regulate BAT can help to develop new nutritional activators. In this paper, we summarize the development and thermogenesis of BAT and thermogenesis-related factors, and review active ingredients in foods that regulate brown fat and their mechanisms of action, and briefly introduce the effects of white adipose tissue (WAT) and BAT on the body’s health. We also discuss recent developments in understanding the role of BAT in regulating energy metabolic balance and various diseases in the body. We hope that the present review will provide a theoretical basis for future development of brown adipose nutritional activators and improvement of individualized healthy dietary management programs in order to prevent and treat various diseases. © 2023 Chinese Chamber of Commerce. All rights reserved.
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页码：278 / 288
页数：10
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  • [1] BRAUER S., Overweight and obesity, Journal of Physiotherapy, 60, 2, (2014)
  • [2] WANG W, SEALE P., Control of brown and beige fat development, Nature Reviews Molecular Cell Biology, 17, 11, pp. 691-702, (2016)
  • [3] CHEN Y, PAN R, PFEIFER A., Regulation of brown and beige fat by microRNAs, Pharmacology & Therapeutics, 170, pp. 1-7, (2017)
  • [4] BARTELT A, HEEREN J., Adipose tissue browning and metabolic health, Nature Reviews Endocrinology, 10, pp. 24-36, (2014)
  • [5] MANN A, THOMPSON A, ROBBINS N, Et al., Localization, identification, and excision of murine adipose depots, Journal of Visualized Experiments, 4, 94, (2014)
  • [6] HELGA S, EMOKE B, LAURA R, Et al., The adipose tissue in farm animals: a proteomi capproach, Current Protein & Peptide Science, 15, 2, pp. 146-155, (2014)
  • [7] SYMONDS M E, POPE M, BUDGE H., The Ontogeny of brown adipose tissue, Annual Review of Nutrition, 35, pp. 295-320, (2015)
  • [8] LEE Y H, MOTTILLO E P, GRANNEMAN J G., Adipose tissue plasticity from WAT to BAT and in between, Biochimica et Biophysica Acta, 1842, 3, pp. 358-369, (2014)
  • [9] BERGAN-ROLLER H E, SHERIDAN M A., The growth hormone signaling system: insights into coordinating the anabolic and catabolic actions of growth hormone, General and Comparative Endocrinology, 258, pp. 119-133, (2018)
  • [10] (2018)
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