NaYF4:Nd3+, Yb3+ Nanocrystals for Temperature Measurement in Biological Environment

被引：0
|
作者：
Xu X. [1 ]
Gu Y. [1 ]
Kong M. [1 ]
Feng W. [1 ]
Li F. [1 ]
机构：
[1] Department of Chemistry, Fudan University, Shanghai
来源：
Zhongguo Xitu Xuebao/Journal of the Chinese Rare Earth Society | 2021年 / 39卷 / 01期
关键词：
In vivo imaging; Rare-earth nanocrystals; Thermometers;
D O I：
10.11785/S1000-4343.20210112
中图分类号：
学科分类号：
摘要：
Nd3+-sensitized NIR-emissive NaYF4: Nd3+, Yb3+ nanocrystals were synthesized by solvothermal method. A decrease in the intensity ratio of 865 nm/980 nm peak was observed as temperature increased tuning the Nd3+ and Yb3+ doping ratio, and comprehensively considering the luminescent intensity and temperature sensitivity, 2% Nd and 20% Yb were found to be the optimal doping concentration. The thermal sensitivity can be increased with Yb3+ doping ratio, with a thermal sensitivity (Sr) of 1.9%•K-1 in cyclohexane and 0.46%•K-1 in aqueous phase. Through the demonstrations of covering meat slices and in vivo laser heating, no obvious change in the intensity ratio was found before and after tissue attenuation, which preliminarily verified the feasibility of using the nanothermometer for measuring temperature in biological systems. © 2021, Editorial Office of Journal of the Chinese Society of Rare Earths. All right reserved.
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页码：181 / 187
页数：6
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