Research Progress and Challenges of 3D Printed Conductive Biological Scaffolds

被引：0
|
作者：
Li W. [1 ]
Zhang G. [1 ]
Yu Z. [1 ]
Han Z. [1 ]
Ma L. [1 ]
Peng Z. [1 ]
Xiao M. [2 ]
Xu L. [3 ,4 ]
Xi Y. [5 ]
Lan H. [1 ]
机构：
[1] Shandong Engineering Research Center for Additive Manufacturing, Qingdao University of Technology, Qingdao
[2] Institute of Cardiovascular Disease, Soochow University, Suzhou
[3] Yantai Affiliated Hospital of Binzhou Medical College, Yantai
[4] Institute of Rehabilitation Engineering Binzhou Medical College, Yantai
[5] The Affiliated Hospital of Qingdao University, Qingdao
来源：
Jixie Gongcheng Xuebao/Journal of Mechanical Engineering | 2023年 / 59卷 / 23期
关键词：
3D printing; cells culture; conductive biological scaffold; conductive materials;
D O I：
10.3901/JME.2023.23.186
中图分类号：
学科分类号：
摘要：
Tissue engineering provides a new solution for regenerative medicine such as repairing or replacing diseased or damaged tissues. In tissue engineering, biological scaffolds, as one of the key elements (carriers), need to simulate the extracellular matrix environment for cell survival as much as possible. They should not only have biocompatibility, biodegradability and mechanical properties, but also have electrical conductivity to conduct bioelectricity. In addition, 3D printing technology has irreplaceable advantages in the manufacturing of complex bionic structures, and has become one of the most popular technologies in the manufacturing of biological scaffolds. Therefore, 3D printing of conductive biological scaffolds has become one of the hot spots in the research of biological scaffolds. In response to this, it is necessary to sort out and analyze the current contents of 3D printing conductive biological scaffolds. The current research status of conductive biological scaffolds is briefly introduced, including conductive materials, conductive methods, 3D printing methods of conductive biological scaffolds, and their typical applications in nerve cells, bone cells and cardiomyocytes. Finally, the future development direction of conductive biological scaffolds is summarized. © 2023 Chinese Mechanical Engineering Society. All rights reserved.
引用
收藏
页码：186 / 210
页数：24
相关论文
共 134 条
  • [1] BEDIR T, USTUNDAG C B, Et al., 3D bioprinting applications in neural tissue engineering for spinal cord injury repair[J], Materials Science and Engineering, 110, (2020)
  • [2] MONIA O, MILENA F, ROBERTO D P, Et al., Biofabrication and bone tissue regeneration：Cell source，approaches ， and challenges[J], Frontiers in Bioengineering and Biotechnology, 5, (2017)
  • [3] FUKADA E, YASUDA I., On the piezoelectric effect of bone[J], Journal of the Physical Society of Japan, 12, 10, pp. 1158-1162, (1957)
  • [4] ALLAHYARI Z, HAGHIGHIPOUR N, MOZTARZADEH F, Et al., Optimization of electrical stimulation parameters for MG-63 cell proliferation on chitosan/functionalized multiwalled carbon nanotube films[J], RSC Advances, 6, 111, (2016)
  • [5] GHOLIZADEH S, MOZTARZADEH F, HAGHIGHIPOUR N, Et al., Preparation and characterization of novel functionalized multiwalled carbon nanotubes/chitosan/ β-Glycerophosphate scaffolds for bone tissue engineering[J], International Journal of Biological Macromolecules, 97, pp. 365-372, (2017)
  • [6] SHAO S, ZHOU S, LI L, Et al., Osteoblast function on electrically conductive electrospun PLA/MWCNTs nanofibers[J], Biomaterials, 32, 11, pp. 2821-2833, (2011)
  • [7] RAVICHANDRAN R, VENUGOPAL J R, SUNDARRAJAN S, Et al., Precipitation of nanohydroxyapatite on PLLA/PBLG/ Collagen nanofibrous structures for the differentiation of adipose derived stem cells to osteogenic lineage[J], Biomaterials, 33, 3, pp. 846-855, (2012)
  • [8] LEVIN M., Large-scale biophysics ： ion flows and regeneration[J], Trends in cell biology, 17, 6, pp. 261-270, (2007)
  • [9] LEVIN M., Bioelectric mechanisms in regeneration：unique aspects and future perspectives[C], Seminars in Cell & Developmental Biology, 20, 5, pp. 543-556, (2009)
  • [10] LEVIN M., Bioelectromagnetics in morphogenesis[J], Bioelectromagnetics, 24, 5, pp. 295-315, (2003)
12345678910