Reconstruction of the aortic pressure waveform using a two-level adaptive transfer function strategy

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作者
Du, Shuo [1 ]
Liu, Wenyan [1 ]
Yao, Yang [2 ]
Sun, Guozhe [3 ]
He, Ying [4 ]
Alastruey, Jordi [5 ,6 ]
Xu, Lisheng [1 ,7 ]
Yao, Yudong [8 ]
Qian, Wei [1 ]
机构
[1] College of Medicine and Biological Information Engineering, Northeastern University, Liaoning, Shenyang,110169, China
[2] School of Information Science and Technology, ShanghaiTech University, Shanghai,201210, China
[3] Department of Cardiology, The First Hospital of China Medical University, Liaoning, Shenyang,110122, China
[4] School of Energy and Power Engineering, Dalian University of Technology, Liaoning, Dalian,116024, China
[5] Department of Biomedical Engineering, King's College, London,SE1 7EH, United Kingdom
[6] World-Class Research Center, Digital Biodesign and Personalized Healthcare, Sechenov First Moscow State Medical University, Moscow,119991, Russia
[7] Neusoft Research of Intelligent Healthcare Technology, Co. Ltd., Liaoning, Shenyang,110169, China
[8] Department of Electrical and Computer Engineering, Stevens Institute of Technology, Hoboken,NJ,07030, United States
基金
中国国家自然科学基金;
关键词
Blood pressure - Blood vessels;
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摘要
Existing studies cannot estimate the high-frequency components of the aortic pressure waveform (APW) practically and reliably. To solve this problem, a two-level adaptive transfer function (ATF) strategy was proposed. Two ATFs were derived from raw and normalized brachial and aortic pressure waveforms. The APW was reconstructed with the amplitude and pulsatility information from the two ATFs. Experimental results showed that our method achieved lower errors for total waveform, diastolic blood pressure, the pressures at the start-systolic and dicrotic-notch points, and three high-frequency-dependent indices including the pressure at inflection point, augmentation index and the time interval from foot to inflection points (3.11 versus 4.24 mmHg, 1.74 versus 1.94 mmHg, 2.56 versus 2.75 mmHg, 6.94 versus 7.47 mmHg, 3.35 versus 3.80 mmHg, 9.56 versus 10.48 % and 24.64 versus 27.73 ms, respectively) compared with traditional generalized transfer function. The proposed method can accurately estimate both the shape and high-frequency components of APW. © 2022 Elsevier Ltd
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