Linkages between Epithelial Microbiota and Host Transcriptome in the Ileum during High-Grain Challenges: Implications for Gut Homeostasis in Goats

被引：0
|
作者：
Jiao, Jinzhen [1 ,2 ]
Zhang, Xiaoli [1 ,3 ]
Wang, Min [1 ,2 ]
Zhou, Chuanshe [1 ,2 ]
Yan, Qiongxian [1 ]
Tan, Zhiliang [1 ,2 ]
机构：
[1] CAS Key Laboratory of Agro-ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Natl. Eng. Lab. for Pollution Control and Waste Utilization in Livestock and Poultry Production, Hunan Provincial Engi
[2] Hunan Co-Innovation Center of Animal Production Safety (CICAPS), Changsha Hunan,410128, China
[3] Graduate University of Chinese Academy of Sciences, Changsha Beijing,100049, China
来源：
Journal of Agricultural and Food Chemistry | 2019年 / 67卷 / 01期
基金：
中国国家自然科学基金;
关键词：
Signal transduction - Vitamins - Carbohydrates - Risk assessment - Proteins - Genes - Biodegradation - Nutrition;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A high-grain (HG) diet can result in ruminal subacute acidosis, which is detrimental to gut health and can lead to decreased productivity. This study investigated the ileal epithelial microbiota and its relationship with host epithelial function in goats fed a HG diet (concentrate/hay, 90:10) and a control diet (concentrate/hay, 55:45), aiming to elucidate the mechanisms involved in ileal adaptation to subacute acidosis. The HG challenge increased the ileal volatile fatty acid concentration (p = 0.030) and altered the ileal epithelial microbiota by increasing (FDR © 2018 American Chemical Society.
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页码：551 / 561
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