During accidents, natural disasters and war, the body of human may suffer serious physical trauma, which will lead uncontrollable massive blood loss. This may further result in ischemic shock and death in the injured. Therefore, fast hemostasis of wound is the key to improve the survival rate of the injured. Fast hemostasis is generally based on using hemostatic materials. Polyhydroxyalkanoates (PHAs), a natural polymer compound, has good biocompatibility, biodegradability and modifying properties. The degradation products of PHAs can also promote the proliferation and differentiation of cells, which can further facilitate healing of wound. Hence PHAs is a good matter of developing hemostatic materials and has attracted extensive attention from biomedical materials researchers. However, PHAs-based materials still have some shortcomings, such as poor toughness, low antibacterial and coagulation performance. Before developing PHAs-based hemostatic materials, the toughness, antibacterial capacity and coagulation performance need to be improved. This review summarizes the research progress of PHAs-based hemostatic materials in recent years, which may provide effective methods and instructions for researching and developing the PHAs-based hemostatic materials. The successful development of PHAs-based hemostatic materials with great socioeconomic value will have significance for emergency of military and sustainable development of mankind. © 2023 Cailiao Daobaoshe/ Materials Review. All rights reserved.
