Expanding luminal epitheliums as cells of origin for prostate cancer

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Yuexi Gu [1 ]
GongHong Wei [1 ,2 ]
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[1] Fudan University Shanghai Cancer Center, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Shanghai Medical College of Fudan University
[2] Biocenter Oulu and Faculty of Biochemistry and Molecular Medicine, University of
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<正>Despite tremendous progress made in human prostate biology over the past few decades, a full picture of prostate lineage hierarchy and its connection to cancer initiation remain to be delineated. Two recent studies published in Nat Genet. [1] and in Science [2] have proflled subpopulations of prostate cells at the single-cell level.
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