Genome editing technology and medical applications

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作者
Liren Wang [1 ]
Bin Zhou [2 ]
Dali Li [1 ]
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[1] Shanghai Frontiers Science Center of Genome Editing and Cell Therapy, Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University
[2] State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of
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<正>It has been over a decade since the groundbreaking debut of CRISPR technology, and it's no exaggeration to say that it has revolutionized many areas of life sciences and biomedical research. CRISPR has significantly reduced the time required to generate animal models, opened new opportunities for developing new models on diverse species, accelerated the speed and expanded the scope of screening strategies, and most importantly, led to the development of new gene therapies for previously untreatable genetic diseases.
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