The role of endosomal cholesterol trafficking protein,StAR-related lipid transfer domain 3(StarD3/MLN64),in BRIN-BD11 insulinoma cells

被引:0
|
作者
Joana Borges Pinto [1 ,2 ]
Annette Graham [1 ]
机构
[1] Department of Life Sciences,School of Health and Life Sciences,Glasgow Caledonian University
[2] WolfsonWohl Cancer Research Centre,Institute of Cancer Sciences,University of
关键词
D O I
暂无
中图分类号
R589 [代谢病];
学科分类号
摘要
<正>Dear Editor,Insulin secretion by pancreatic(3-cells is modulated by altering the cellular content and distribution of cholesterol,which is tightly regulated by a network of transcription factors,enzymes,receptors,transporters and cholesterol trafficking proteins.Inhibition of cellular biosynthesis by'statin'
引用
收藏
页码:833 / 838
页数:6
相关论文
共 8 条
  • [1] The role of endosomal cholesterol trafficking protein, StAR-related lipid transfer domain 3 (StarD3/MLN64), in BRIN-BD11 insulinoma cells
    Pinto, Joana Borges
    Graham, Annette
    PROTEIN & CELL, 2016, 7 (11) : 833 - 838
  • [2] Cholesterol interaction with the related steroidogenic acute regulatory lipid-transfer (START) domains of StAR (STARD1) and MLN64 (STARD3)
    Reitz, Julian
    Gehrig-Burger, Katja
    Strauss, Jerome F., III
    Gimpl, Gerald
    FEBS JOURNAL, 2008, 275 (08) : 1790 - 1802
  • [3] Crystal structure of the Mus musculus cholesterol-regulated START protein 4 (StarD4) containing a StAR-related lipid transfer domain
    Romanowski, MJ
    Soccio, RE
    Breslow, JL
    Burley, SK
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (10) : 6949 - 6954
  • [4] StAR-related lipid transfer domain protein 3 (STARD3) regulates HER2 and promotes HER2-positive breast cancer progression through interaction with HSP90 and SRC signaling
    Binh, Doan Huu Nhat
    Cheng, Tzu-Chun
    Tu, Shih-Hsin
    Liao, You-Cheng
    Yang, Yi-Yuan
    Chen, Li-Ching
    Ho, Yuan-Soon
    AMERICAN JOURNAL OF CANCER RESEARCH, 2023, 13 (11): : 5151 - +
  • [5] Stard 3 (Steroidogenic Acute Regulatory-Related Lipid Transfer Domain-Containing Protein 3) Play Important Role in Preadipocyte Differentiation
    Chen, Zhonge
    Tang, Yanhua
    Jiang, Wenyong
    Zhou, Xiaoqian
    JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING, 2022, 12 (04) : 827 - 833
  • [6] Steroidogenic Acute Regulatory (StAR)-Related Lipid Transfer Domain Protein 5 (STARD5) expression is associated with cholesterol content of human kidney proximal tubule cells
    Clark, Barbara J.
    Meier, Renate K.
    Khundmiri, Syed J.
    Lederer, Eleanor D.
    FASEB JOURNAL, 2011, 25
  • [7] Elevated Levels of StAR-Related Lipid Transfer Protein 3 Alter Cholesterol Balance and Adhesiveness of Breast Cancer Cells Potential Mechanisms Contributing to Progression of HER2-Positive Breast Cancers
    Vassilev, Boris
    Sihto, Harri
    Li, Shiqian
    Holtta-Vuori, Maarit
    Ilola, Jaakko
    Lundin, Johan
    Isola, Jorma
    Kellokumpu-Lehtinen, Pirkko-Liisa
    Joensuu, Heikki
    Ikonen, Elina
    AMERICAN JOURNAL OF PATHOLOGY, 2015, 185 (04): : 987 - 1000
  • [8] Endoplasmic Reticulum Stress Enhances Steroidogenic Acute Regulatory (StAR)-Related Lipid Transfer Domain Protein 5 (STARD5) Expression and Cholesterol Efflux in HKC-8 Human Renal Proximal Tubule Cells
    Clark, Barbara J.
    Chen, Yuchyu
    Brown, Ryan
    Carroll, Julie A.
    Blaker, Kristen M.
    Meier, Renate K.
    Khundmiri, Syed J.
    Lederer, Eleanor D.
    FASEB JOURNAL, 2010, 24