Death receptor 6 is a novel plasmacytoid dendritic cell-specific receptor and modulates type Ⅰ interferon production

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作者
Jingyun Li [1 ,2 ]
Qiumei Du [1 ,2 ]
Rui Hu [1 ,2 ]
Yanbing Wang [1 ]
Xiangyun Yin [1 ,2 ]
Haisheng Yu [1 ,2 ]
Peishuang Du [1 ]
Jol Plumas [3 ]
Laurence Chaperot [3 ]
Yongjun Liu [1 ,4 ]
Liguo Zhang [1 ]
机构
[1] Key Laboratory of Immunity and Infection,Institute of Biophysics,Chinese Academy of Sciences
[2] University of Chinese Academy of Sciences
[3] Department of Research and Development,Etablissement Francais du Sang Rhone-Alpes Grenoble
[4] Baylor Institute for Immunology Research,Baylor Research
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<正>Dear Editor,Plasmacytoid dendritic cells(pDCs)are the professional type I interferon-producing cells of the immune system,which rapidly produce massive amounts of type I interferons(IFN-I)in response to viruses or other nucleic acids ligands through selectively expressed toll-like receptor(TLR)-7 and TLR9(Siegal et al.,1999).The activation of pDCs not only
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页码:291 / 294
页数:4
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