P2X7 receptor inhibition of microglia attenuates repeated social defeat induced monocyte recruitment and anxiety-like behavior

被引:0
|
作者
Biltz, Rebecca [1 ]
Swanson, Samuel [1 ]
Draime, Natalie [1 ]
Davis, Amara [1 ]
Yin, Weyuan [1 ]
Goodman, Ethan [1 ]
Gallagher, Natalie [1 ]
Bhattacharya, Anindya [2 ]
Sheridan, John [3 ]
Godbout, Jon [1 ]
机构
[1] Ohio State Univ, Dept Neurosci, Columbus, OH 43210 USA
[2] Janssen Res & Dev, Neurosci, Raritan, NJ USA
[3] Ohio State Univ, Div Biosci, Columbus, OH 43210 USA
关键词
D O I
10.1016/j.bbi.2024.01.061
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
PS1-09
引用
收藏
页码:18 / 18
页数:1
相关论文
共 50 条
  • [1] Antagonism of the brain P2X7 ion channel attenuates repeated social defeat induced microglia reactivity, monocyte recruitment and anxiety-like behavior in male mice
    Biltz, Rebecca G.
    Swanson, Samuel P.
    Draime, Natalie
    Davis, Amara C.
    Yin, Wenyuan
    Goodman, Ethan J.
    Gallagher, Natalie R.
    Bhattacharya, Anindya
    Sheridan, John F.
    Godbout, Jonathan P.
    BRAIN BEHAVIOR AND IMMUNITY, 2024, 115 : 356 - 373
  • [2] β-Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat
    Wohleb, Eric S.
    Hanke, Mark L.
    Corona, Angela W.
    Powell, Nicole D.
    Stiner, La'Tonia M.
    Bailey, Michael T.
    Nelson, Randy J.
    Godbout, Jonathan P.
    Sheridan, John F.
    JOURNAL OF NEUROSCIENCE, 2011, 31 (17): : 6277 - 6288
  • [3] Repeated social defeat-induced anxiety-like behavioural and neurobiological alterations in rats
    Benoliel, J.
    Zeau, B.
    Rivat, C.
    Blugeot, A.
    Becker, C.
    EUROPEAN NEUROPSYCHOPHARMACOLOGY, 2007, 17 : S193 - S194
  • [4] Repeated social defeat in female mice induces anxiety-like behavior associated with enhanced myelopoiesis and increased monocyte accumulation in the brain
    Yin, Wenyuan
    Gallagher, Natalie R.
    Sawicki, Caroline M.
    McKim, Daniel B.
    Godbout, Jonathan P.
    Sheridan, John F.
    BRAIN BEHAVIOR AND IMMUNITY, 2019, 78 : 131 - 142
  • [5] P2X7 receptor inhibition attenuates cancer-induced bone pain in rats
    Falk, Sarah
    Clausen, Rasmus P.
    Dickenson, Anthony H.
    Heegaard, Anne-Marie
    PURINERGIC SIGNALLING, 2014, 10 (04) : 849 - 849
  • [6] The role of the P2X7 receptor in microglia in relation to glaucoma
    Felgate, M.
    Stokes, L.
    Broadway, D. C.
    Sanderson, J.
    BRITISH JOURNAL OF PHARMACOLOGY, 2019, 176 (16) : 3056 - 3056
  • [7] The role of the P2X7 receptor in microglia in relation to glaucoma
    Felgate, Matthew
    Stokes, Leanne
    Broadway, David C.
    Sanderson, Julie
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2018, 59 (09)
  • [8] Microglia: Proliferation and activation driven by the P2X7 receptor
    Monif, Mastura
    Burnstock, Geoffrey
    Williams, David A.
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2010, 42 (11): : 1753 - 1756
  • [9] Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2
    Sabrina Francesca Lisboa
    Anzela Niraula
    Leonardo Barbosa Resstel
    Francisco Silveira Guimaraes
    Jonathan P. Godbout
    John F. Sheridan
    Neuropsychopharmacology, 2018, 43 : 1924 - 1933
  • [10] Repeated social defeat-induced neuroinflammation, anxiety-like behavior and resistance to fear extinction were attenuated by the cannabinoid receptor agonist WIN55,212-2
    Lisboa, Sabrina Francesca
    Niraula, Anzela
    Resstel, Leonardo Barbosa
    Guimaraes, Francisco Silveira
    Godbout, Jonathan P.
    Sheridan, John F.
    NEUROPSYCHOPHARMACOLOGY, 2018, 43 (09) : 1924 - 1933