A Novel Point Mutation of the Human Glucocorticoid Receptor Gene Causes Primary Generalized Glucocorticoid Resistance through Reduced Flexibility of Helix 10 of the Ligand-Binding Domain of the Receptor and Decreased Affinity for the Ligand

被引：0
|
作者：
Nicolaides, Nicolas C. [1 ]
Geer, Eliza B. [2 ]
Vlachakis, Dimitrios [1 ]
Sertedaki, Amalia [3 ]
Bakopoulou, Ioanna [3 ]
Kossida, Sophia [1 ]
Chrousos, George P. [3 ]
Charmandari, Evangelia [3 ]
机构：
[1] Acad Athens, Biomed Res Fdn, Athens, Greece
[2] Mt Sinai Sch Med, New York, NY USA
[3] Univ Athens, Sch Med, Athens, Greece
来源：
ENDOCRINE REVIEWS | 2014年 / 35卷 / 03期
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中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
MON-0804
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页数：2
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