Treatment of [99mTc]Tc-hydroxy-diphosphonate ([99mTc]Tc-HDP) extravasation using hyaluronidase

被引：0
|
作者：
Doornhof, Kevin R. [1 ]
de Lussanet de la Sabloniere, Quido [1 ]
Koolen, Stijn L. W. [1 ]
Konijnenberg, Mark W. [1 ]
机构：
[1] Erasmus MC, Univ Med Ctr Rotterdam, Dept Radiol & Nucl Med, Dr Molewaterplein 40, NL-3015 GD Rotterdam, Netherlands
来源：
PHARMACOLOGY RESEARCH & PERSPECTIVES | 2024年 / 12卷 / 04期
关键词：
bone scintigraphy; extravasation; radiology [99mTc]Tc-HDP; RADIOPHARMACEUTICAL EXTRAVASATION;
D O I：
10.1002/prp2.1232
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Extravasation of 99mTc-labeled radiopharmaceuticals is generally considered to require no specific intervention. In the presented case, the use of hyaluronidase could have minimized the adverse effects resulting from such an extravasation. Currently, no guidelines exist regarding the use of hyaluronidase after extravasation of [99mTc]Tc-HDP. Considering the low risk of administering hyaluronidase, it should be considered to limit the risk of injury after extravasation of [99mTc]Tc-HDP.
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页数：3
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