Risk of gastrointestinal bleeding in Asian patients receiving oral anticoagulants for stroke prevention in atrial fibrillation

被引:0
|
作者
Diaz, Alejandro Bimbo [1 ]
Chow, Jeremy [2 ]
Hoo, Fan Kee [3 ]
Keong, Gary Lee Chin [4 ]
Venketasubramanian, Narayanaswamy [5 ]
Rey, Nannette [6 ]
Rogelio, Gregorio [7 ]
Mehta, Radhika [8 ]
机构
[1] Univ Santo Tomas Hosp, Manila, Philippines
[2] Asian Heart & Vasc Ctr, Singapore, Singapore
[3] Univ Putra Malaysia, Serdang, Malaysia
[4] Thomson Hosp Kota Damansara, Petaling Jaya, Malaysia
[5] Raffles Hosp, Singapore, Singapore
[6] De La Salle Med & Hlth Sci Inst, Dasmarinas Cavite, Philippines
[7] St Lukes Med Ctr, Quezon City, Philippines
[8] Menarini Asia Pacific Pte Ltd, Singapore, Singapore
关键词
Asian patients; atrial fibrillation; edoxaban; gastrointestinal bleeding; non-vitamin K oral anticoagulant; Southeast Asia; stroke; WARFARIN; EDOXABAN; DABIGATRAN; OUTCOMES; METAANALYSIS;
D O I
10.7573/dic.2024-5-5
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for stroke prevention in atrial fibrillation. At the Asia Pacific Advancing Patient care with EdoXaban 2023 meeting, experts shared insights on gastrointestinal bleeding with NOACs for stroke prevention in atrial fibrillation in Asian clinical practice, where NOACs have gained widespread acceptance due to their favourable profiles. Gastrointestinal bleeding risk varies amongst NOACs, emphasizing the importance of diligent patient assessment, dosage selection and vigilant monitoring. Edoxaban emerged as a viable option with a low gastrointestinal bleeding risk profile in Asian compared with non-Asian patients, supporting its continued clinical utilization for appropriate patients.
引用
收藏
页数:15
相关论文
共 50 条
  • [1] Guideline Adherence: Are Patients with Atrial Fibrillation Receiving Oral Anticoagulants for Stroke Prevention?
    Po, Helen L.
    Yu, Hui Fen
    Lin, Hsiao Chu
    Lin, Ya Ju
    Chen, Yi Min
    Chou, Chao Liang
    Chen, Lu An
    Huang, Ying Ting
    CEREBROVASCULAR DISEASES, 2014, 38 : 96 - 96
  • [2] Oral Anticoagulants for Nonvalvular Atrial Fibrillation in Patients With High Risk of Gastrointestinal Bleeding
    Lip, Gregory Y. H.
    Keshishian, Allison, V
    Zhang, Yan
    Kang, Amiee
    Dhamane, Amol D.
    Luo, Xuemei
    Klem, Christian
    Ferri, Mauricio
    Jiang, Jenny
    Yuce, Huseyin
    Deitelzweig, Steven
    JAMA NETWORK OPEN, 2021, 4 (08) : E2120064
  • [3] Minimizing bleeding risk in patients receiving direct oral anticoagulants for stroke prevention
    Habert, Jeffrey Steven
    INTERNATIONAL JOURNAL OF GENERAL MEDICINE, 2016, 9 : 337 - 347
  • [4] Meta-analysis of Stroke and Bleeding Risk in Patients with Various Atrial Fibrillation Patterns Receiving Oral Anticoagulants
    Zhang, Weifang
    Xiong, Youwen
    Yu, Lingling
    Xiong, Aizhen
    Bao, Huihui
    Cheng, Xiaoshu
    AMERICAN JOURNAL OF CARDIOLOGY, 2019, 123 (06): : 922 - 928
  • [5] Comparative Bleeding Risk in Older Patients With HIV and Atrial Fibrillation Receiving Oral Anticoagulants
    Quinlan, Claire M.
    Avorn, Jerry
    Kesselheim, Aaron S.
    Singer, Daniel E.
    Zhang, Yichi
    Cervone, Alex
    Lin, Kueiyu Joshua
    JAMA INTERNAL MEDICINE, 2025,
  • [6] Stroke prevention with direct oral anticoagulants in high-risk elderly atrial fibrillation patients at increased bleeding risk
    Chao, Tze-Fan
    Chan, Yi-Hsin
    Chiang, Chern-En
    Tuan, Ta-Chuan
    Liao, Jo-Nan
    Chen, Tzeng-Ji
    Lip, Gregory Y. H.
    Chen, Shih-Ann
    EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES, 2022, 8 (07) : 730 - 738
  • [7] Balancing Efficacy and Bleeding Risk in the Prevention of Stroke Due to Atrial Fibrillation with Newer Oral Anticoagulants
    Agarwal, M. B.
    Verma, Subhash
    Mahapatra, Manoranjan
    Tripathi, A. K.
    Bhave, Abhay
    Deshpande, Anand
    Vora, Amit
    Dalal, Jamshed J.
    Shah, A. B.
    Bichu, S.
    INDIAN JOURNAL OF HEMATOLOGY AND BLOOD TRANSFUSION, 2012, 28 (03) : 129 - 143
  • [8] Balancing Efficacy and Bleeding Risk in the Prevention of Stroke Due to Atrial Fibrillation with Newer Oral Anticoagulants
    M. B. Agarwal
    Subhash Verma
    Manoranjan Mahapatra
    A. K. Tripathi
    Abhay Bhave
    Anand Deshpande
    Amit Vora
    Jamshed J. Dalal
    A. B. Shah
    S. Bichu
    Indian Journal of Hematology and Blood Transfusion, 2012, 28 : 129 - 143
  • [9] Comparison of clinical performance of four gastrointestinal bleeding risk scores in Chinese patients with atrial fibrillation receiving oral anticoagulants
    Mei-na Lv
    Xiao-chun Zheng
    Hong-qin Zhang
    Fang-da Xu
    Ting-ting Wu
    Wen-jun Chen
    Xiao-tong Xia
    Jing-lan Fu
    Shao-jun Jiang
    Jin-hua Zhang
    Journal of Thrombosis and Thrombolysis, 2021, 51 : 136 - 142
  • [10] Comparison of clinical performance of four gastrointestinal bleeding risk scores in Chinese patients with atrial fibrillation receiving oral anticoagulants
    Lv, Mei-na
    Zheng, Xiao-chun
    Zhang, Hong-qin
    Xu, Fang-da
    Wu, Ting-ting
    Chen, Wen-jun
    Xia, Xiao-tong
    Fu, Jing-lan
    Jiang, Shao-jun
    Zhang, Jin-hua
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2021, 51 (01) : 136 - 142