The brittleness of ceramics restricts their engineering application. Prestressing is promising to solve the problem, yet still lacks enough attention and extensive investigation. This work proposes the idea of macro-scale and micro-scale prestressed ceramics: to form compressive prestress in macro- or micro-scale range in the ceramics by designed additional force, which offsets the fracture stress at the crack tips, then enhances the strength of ceramics. The macro-scale prestressed ceramic has a designed long-range ordering stress distribution in a large scale, similar to the reinforced concrete and tempered glass. The micro-scale ceramic has a designed short-range ordered stress distribution, similar to that in the natural biomaterials. Strategies constructing the macro-scale and micro-scale prestressed ceramics are planned. Future research interests and challenges are prospected for developing the mechanical properties of ceramics. This work proposes the idea of macro-scale and micro-scale prestressed ceramics, that is, to form macro- or micro-scale compressive prestress to offset the fracture stress at the crack tips. The graph presents typical structures to construct macro- or micro-scale prestressed ceramics, including the elemental model and assembled model. Future research interests and challenges are further prospected in this paper.image