Multiple Instance Learning Research for the Classification of Lung Cancer in CT Diagnosis

Lung cancer with the highest mortality rate has attracted public attention. For the difficulty of treating lung cancer increases sharply over time, detecting lung cancer symptoms early on chest computed tomography (CT) is crucial for the subsequent treatment. The number of slices can affect the accuracy of lung cancer examination, so a deep multiple instance learning algorithm was designed and proposed to classify lung cancer effectively. First, feature information is extracted in the patient 3D CT image using the high and low frequency high dimensional features (HLFHD) to balance local detail and global overall information of images. Secondly, to find the decisive features, a sliding recurrent neural network (MSRNN) module is used to take into account the feature variations between slices. The experimental studies in this paper were constructed on two public datasets, namely, CIA and CC-CCII data. Finally, the experimental results show that the proposed algorithm can achieve an ACC of 0.97 and an AUC of 0.99 on the datasets. These results suggest that the proposed algorithm is well suited for lung cancer classification of any number of CT slices, and it can be effectively employed in computer-aided systems to achieve state-of-the-art performance.