AimTo explore the underlying motivations behind young individuals' use of electronic cigarettes and to uncover gender differences in usage patterns.Subject and methodsThe quantitative study sample included individuals up to 25 years old, without differentiation based on gender or specific location. A comprehensive online survey was conducted in November and December of 2022 using a questionnaire designed by the author. Following the preparation of the online survey, it was shared on youth-oriented social platforms.ResultsThe survey, which included 1335 respondents up to 25 years old, revealed a significant gender difference in initiation patterns, with a higher percentage of females (84.2%) than males (80.1%) trying electronic cigarettes, often starting in adolescence, and with 80.3% reporting recent use, indicating widespread consumption. The survey also found a preference for higher nicotine concentrations and different acquisition patterns between genders, with males preferring specialty shops and online sources, and females more often obtaining electronic cigarettes through social connections. The main reasons for starting were social influence, stress relief and flavour variety. Post-use reported symptoms varied by gender, indicating distinct physiological impacts.ConclusionThe findings reveal that females experiment with electronic cigarettes more frequently and at younger ages than males, indicating a concerning trend towards nicotine addiction among youths, particularly due to their regular use and preference for high nicotine content. Moreover, gender-specific differences in symptoms following vaping require personalized health education and interventions to address these distinct physiological reactions effectively.