Developments and Controversies in Invasive Diagnosis of Coronary Microvascular Dysfunction in Angina With Nonobstructive Coronary Arteries

被引：3

作者：

Denby, Kara J. ^{[1
]}

Zmaili, Mohammad ^{[2
]}

Datta, Sudarshana ^{[3
]}

Das, Thomas ^{[2
]}

Ellis, Stephen ^{[2
]}

Ziada, Khaled ^{[2
]}

Lerman, Amir ^{[4
]}

Raphael, Claire E. ^{[4
]}

机构：

[1] St Alphonsus Reg Med Ctr, Dept Cardiovasc Med, Boise, ID USA

[2] Cleveland Clin Fdn, Heart Vasc & Thorac Inst, Dept Cardiovasc Med, Cleveland, OH USA

[3] Texas Med Ctr, Mem Hermann Heart & Vasc Inst, Houston, TX USA

[4] Mayo Clin, Dept Cardiovasc Med, 200 First St SW, Rochester, MN 55905 USA

来源：

MAYO CLINIC PROCEEDINGS | 2024年 / 99卷 / 09期

关键词：

ASSESS FLOW RESERVE; BLOOD-FLOW; MICROCIRCULATORY RESISTANCE; PROGNOSTIC VALUE; STABLE ANGINA; INTERNATIONAL STANDARDIZATION; MYOCARDIAL-PERFUSION; CLINICAL-OUTCOMES; CHEST-PAIN; THERMODILUTION;

D O I：

10.1016/j.mayocp.2024.04.022

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Approximately half of all coronary angiograms performed for angina do not show obstructive coronary artery disease, and many of these patients have coronary microvascular dysfunction (CMD). Invasive testing for CMD has increased with the advent and wider availability of thermodilution systems. We review CMD pathophysiology and invasive diagnostic testing using the Doppler and thermodilution systems. We report the results of a PubMed search of invasive microvascular testing and discuss limitations of current diagnostic algorithms in the diagnosis of CMD, including controversies regarding the optimal cutoff value for abnormal coronary flow reserve, use of microvascular resistance indices, and options for increasing sensitivity of testing. (c) 2024 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies

引用

页码：1469 / 1481

页数：13

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