Nano-based Herbal Medicine: A New Candidate for Prostate Cancer Treatment?

被引:0
|
作者
Pouryousefi-koodehi, Tayebe [1 ]
Kahrizi, Mohammad Saeed [2 ]
Roghani-Shahraki, Hossein [3 ]
Rezaei-Tazangi, Fatemeh [4 ]
Arefnezhad, Reza [5 ]
Motedayyen, Hossein [6 ]
机构
[1] Milad Hosp, Dept Emergency, Tehran, Iran
[2] Alborz Univ Med Sci, Dept Surg, Karaj, Alborz, Iran
[3] Shiraz Univ Med Sci, Student Res Comm, Shiraz, Iran
[4] Fasa Univ Med Sci, Sch Med, Dept Anat, Fasa, Iran
[5] Coenzyme R Res Inst, Tehran, Iran
[6] Kashan Univ Med Sci, Shahid Beheshti Hosp, Autoimmune Dis Res Ctr, Kashan, Iran
关键词
Curcumin; quercetin; resveratrol; herbal remedy; nanomaterials; prostate cancer (PCa); LOADED PLGA NANOPARTICLES; IN-VITRO; CLINICAL TRANSLATION; ANTICANCER ACTIVITY; CURCUMIN; RESVERATROL; QUERCETIN; DELIVERY; INFLAMMATION; NANOEMULSIONS;
D O I
10.2174/2215083810666230815142928
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
Background Prostate cancer (PCa) is known as the fifth reason for cancer-related deaths and involves a considerable population of men globally. In PCa, pluriform neoplasm with different cancer patterns is formed. Metastases have a substantial role in disease mortality, and lung, liver, and bone are among the common organs for metastasis. In spite of multiple attempts by researchers, it has not been recommended a safe and suitable approach against PCa so far.Results Fortunately, herbal remedies have opened a novel window in order to treat several cancers, such as PCa; however, there are some barriers regarding this curative method, like low bioavailability and absorption and low water solubility. On the contrary, some nano-based formulations have revealed a potential ability to overcome these limitations, and it seems that the co-use of herbal products and nanoformulations provides a good opportunity for treating PCa.Conclusion In this study, we argued about the therapeutic aspects of some nanoformulations of popular herbal products, such as curcumin, quercetin, and resveratrol, against PCa.
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页数:10
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