Genetic variants of NQO1 affect the expression and activity of the protein, which determines the efficacy of idebenone treatment in Leber's hereditary optic neuropathy

被引：0
|
作者：
Del Dotto, Valentina [1 ]
Aleo, Serena J. [1 ]
Romagnoli, Martina [1 ]
Fiorini, Claudio [1 ]
Capirossi, Giada [2 ]
Peron, Camille [3 ]
Fasano, Chiara [3 ]
Maresca, Alessandra [1 ]
Caporali, Leonardo [1 ]
Capristo, Mariantonietta [1 ]
Tropeano, Concetta V. [1 ]
Zanna, Claudia [2 ]
Porcelli, Anna M. [4 ]
Tioli, Gaia [4 ]
Amore, Giulia [2 ]
La Morgia, Chiara [1 ,2 ]
Tiranti, Valeria [3 ]
Carelli, Valerio [1 ,2 ]
Ghelli, Anna [1 ,4 ]
机构：
[1] Univ Bologna, Dept Biomed & Neuromotor Sci, Bologna, Italy
[2] IRCCS Ist Sci Neurol Bologna, Programma Neurogenet, Bologna, Italy
[3] Fdn IRCCS Ist Neurol Carlo Besta, Unit Med Genet & Neurogenet, Milan, Italy
[4] Univ Bologna, Dept Pharm & Biotechnol, Bologna, Italy
来源：
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS | 2024年 / 1865卷
关键词：
D O I：
10.1016/j.bbabio.2024.149470
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
T23 P-4
引用
收藏
页码：137 / 137
页数：1
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