Encorafenib plus binimetinib for BRAF V600E-mutant metastatic NSCLC: clinical implications of the phase 2 PHAROS study

被引:0
|
作者
Ramalingam, Suresh S. [1 ]
Carlisle, Jennifer W. [1 ]
机构
[1] Emory Univ, Sch Med, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA 30322 USA
关键词
binimetinib; BRAF; encorafenib; non-small cell lung cancer; podcast; CELL LUNG-CANCER; OPEN-LABEL; MUTATIONS; DABRAFENIB; EFFICACY; FEATURES; IMMUNOTHERAPY; MULTICENTER; VEMURAFENIB; INHIBITORS;
D O I
10.1080/14796694.2024.2391270
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Drs. Ramalingam and Carlisle discuss the incidence and pathophysiology of BRAF V600E-mutant metastatic non-small cell lung cancer and current treatment options. The podcast provides an overview of the data from the recent Pfizer-sponsored phase 2 PHAROS (NCT03915951) study, which were the basis for the recent US Food and Drug Administration approval of encorafenib plus binimetinib for BRAF V600E-mutant metastatic non-small cell lung cancer.
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页数:6
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