Amyloid β, γ-secretase, and familial Alzheimer's disease

被引：0
|
作者：
Potier, Marie-Claude [1 ]
Steiner, Harald [2 ,3 ]
Chavez-Gutierrez, Lucia [4 ]
机构：
[1] Sorbonne Univ, Hop Pitie Salpetriere, AP HP, Inst Cerveau Paris Brain Inst ICM,Inst Natl Sante, F-75013 Paris, France
[2] Ludwig Maximilian Univ Munich, Biomed Ctr, Div Metab Biochem, Munich, Germany
[3] German Ctr Neurodegenerat Dis, Munich, Germany
[4] Katholieke Univ Leuven, Ctr Brain & Dis Res, Vlaams Inst Biotechnol, Leuven, Belgium
来源：
LANCET NEUROLOGY | 2024年 / 23卷 / 09期
关键词：
MUTATIONS;
D O I：
10.1016/S14744422(24)002928
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
引用
收藏
页码：852 / 853
页数：2
相关论文
共 50 条
  • [1] Alzheimer's disease:: β-amyloid and γ-secretase
    Iwatsubo, Takeshi
    [J]. NEUROBIOLOGY OF AGING, 2008, 29 : S13 - S13
  • [2] Dysfunctional -Secretase in Familial Alzheimer's Disease
    Wolfe, Michael S.
    [J]. NEUROCHEMICAL RESEARCH, 2019, 44 (01) : 5 - 11
  • [3] Targeting γ-secretase for familial Alzheimer’s disease
    Michael S. Wolfe
    [J]. Medicinal Chemistry Research, 2021, 30 : 1321 - 1327
  • [4] Targeting γ-secretase for familial Alzheimer's disease
    Wolfe, Michael S.
    [J]. MEDICINAL CHEMISTRY RESEARCH, 2021, 30 (07) : 1321 - 1327
  • [5] Dysfunctional γ-Secretase in Familial Alzheimer’s Disease
    Michael S. Wolfe
    [J]. Neurochemical Research, 2019, 44 : 5 - 11
  • [6] Alzheimer disease and amyloid-secretase
    Koike, H
    Ishiura, S
    [J]. NIPPON NOGEIKAGAKU KAISHI-JOURNAL OF THE JAPAN SOCIETY FOR BIOSCIENCE BIOTECHNOLOGY AND AGROCHEMISTRY, 2000, 74 (09): : 999 - 1003
  • [7] Increased expression of the amyloid precursor β-secretase in Alzheimer's disease
    Holsinger, RMD
    McLean, CA
    Beyreuther, K
    Masters, CL
    Evin, G
    [J]. ANNALS OF NEUROLOGY, 2002, 51 (06) : 783 - 786
  • [8] Familial Alzheimer's disease mutations in amyloid protein precursor alter proteolysis by γ-secretase to increase amyloid β-peptides of ≥45 residues
    Devkota, Sujan
    Williams, Todd D.
    Wolfe, Michael S.
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 2021, 296
  • [9] β-Secretase cleavage of the amyloid precursor protein mediates neuronal apoptosis caused by familial Alzheimer's disease mutations
    McPhie, DL
    Golde, T
    Eckman, CB
    Yager, D
    Brant, JB
    Neve, RL
    [J]. MOLECULAR BRAIN RESEARCH, 2001, 97 (01): : 103 - 113
  • [10] Effects of familial Alzheimer's disease mutations on gamma-secretase activation for cleavage of amyloid precursor protein
    Do, Hung N.
    Devkota, Sujan
    Bhattarai, Apurba
    Wolfe, Michael S.
    Miao, Yinglong
    [J]. BIOPHYSICAL JOURNAL, 2023, 122 (03) : 507A - 507A
12345