Risk factors and correlates of protection against XBB SARS-CoV-2 infection among health care workers

被引：0

作者：

Canetti, Michal ^{[1
,2
]}

Barda, Noam ^{[1
,3
,4
,5
]}

Lustig, Yaniv ^{[1
,2
,6
]}

Weiss-Ottolenghi, Yael ^{[1
,2
,7
]}

Indenbaum, Victoria ^{[2
,6
]}

Peretz, Yovel ^{[1
,7
]}

Zuckerman, Neta ^{[6
]}

Asraf, Keren ^{[2
,8
]}

Amit, Sharon ^{[2
,9
]}

Kreiss, Yitshak ^{[2
,10
]}

Regev-Yochay, Gili ^{[1
,2
,7
]}

机构：

[1] Sheba Med Ctr, Sheba Pandem Preparedness Res Inst, Ramat Gan, Israel

[2] Tel Aviv Univ, Sackler Sch Med, Tel Aviv, Israel

[3] Sheba Med Ctr, ARC Innovat Ctr, Tel Hashomer, Ramat Gan, Israel

[4] Ben Gurion Univ Negev, Software & Informat Syst Engn, Beer Sheva, Israel

[5] Ben Gurion Univ Negev, Epidemiol Biostat & Community Hlth Sci, Beer Sheva, Israel

[6] Minist Hlth, Publ Hlth Serv, Cent Virol Lab, Tel Hashomer, Ramat Gan, Israel

[7] Sheba Med Ctr, Infect Prevent & Control Unit, Tel Hashomer, Ramat Gan, Israel

[8] Sheba Med Ctr, Dworman Automated Mega Lab, Tel Hashomer, Ramat Gan, Israel

[9] Sheba Med Ctr, Clin Microbiol, Tel Hashomer, Ramat Gan, Israel

[10] Sheba Med Ctr, Gen Management, Tel Hashomer, Ramat Gan, Israel

来源：

VACCINE | 2024年 / 42卷 / 26期

关键词：

COVID-19; Omicron; XBB; Correlates of protection;

D O I：

10.1016/j.vaccine.2024.126308

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Correlates of protection for recent emerging SARS-CoV-2 variants have not been determined. In this test-negative case-control study, we report lower odds of infection with XBB variants among those boosted during the last six months. Additionally, we demonstrate that XBB-specific neutralizing antibodies are independent correlates of protection.

引用

页数：5

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