Anion Relay Chemistry Enables Stereoselective Carbonyl-Alkyne Metathesis Reactions

被引：4
|
作者：
Li, Rui-Peng [1 ]
Xu, Xiangrong [1 ]
Zhang, Zhuzhu [1 ]
Gong, Xiaomeng [1 ]
Tang, Shouchu [1 ]
机构：
[1] Lanzhou Univ, Sch Pharm, Lanzhou 730000, Peoples R China
来源：
ORGANIC LETTERS | 2024年 / 26卷 / 36期
关键词：
ACCESS;
D O I：
10.1021/acs.orglett.4c02695
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Dithiane chemistry is increasingly advantageous in the development of novel anion relay chemistry (ARC) modes that harness their umpolung properties to address new chemical challenges. Herein, we report the use of an ARC strategy to promote the regioselective carbonyl alkyne metathesis (CAM) of various carbonyl compounds with alkynyl 1,3-dithianes. Notably, this ARC transformation provides a platform for obtaining stereodefined polysubstituted 1,3-dienes.
引用
收藏
页码：7601 / 7606
页数：6
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