Identification of a new flavonol glucuronide from Alpinia oxyphylla

被引：0
|
作者：
Zhao, Jiao [1 ]
Ji, Dawei [2 ]
Chen, Qiang [3 ]
Dai, Mengzhu [4 ]
Wang, Qun [5 ]
Xu, Hongtao [6 ]
Ma, Cong [7 ]
机构：
[1] Dalian Univ Technol, China Med Univ, Liaoning Canc Hosp & Inst, Dept Gynecol,Canc Hosp, Shenyang, Peoples R China
[2] Fourth Peoples Hosp Shenyang, Dept Gen Surg, Shenyang, Peoples R China
[3] Liaoning Univ Tradit Chinese Med, Marxist Acad, Shenyang, Peoples R China
[4] Liaoning Univ Tradit Chinese Med, Grad Sch, Shenyang, Peoples R China
[5] Liaoning Univ Tradit Chinese Med, Key Lab MoE TCM Viscera State Theory & Apps, Shenyang, Peoples R China
[6] Dalian Univ Technol, China Med Univ, Liaoning Canc Hosp & Inst, Dept Anesthesiol,Canc Hosp, Shenyang, Peoples R China
[7] Liaoning Univ Tradit Chinese Med, Clin Coll 1, Shenyang, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2024年
关键词：
Flavonoid glycoside; U251; NMR; EXTRACTS;
D O I：
10.1080/14786419.2024.2386129
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
The fruits of Alpinia oxyphylla has been used a famous traditional Chinese medicine. A chemical investigation on the fruits of A. oxyphylla resulted in the isolation of one new acetylated flavanol glucuronide (1) and two known compounds (2-3). Compound 1 displayed a weak inhibitory effect on U251 cells with the IC50 value 128.51 mu M while the positive control drug temozolomide exhibited the IC50 value 35.37 mu M.
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页数：4
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