Plasmonic circular dichroism-based metal ion detection using gold nanorod-DNA complexes

被引:1
|
作者
Shi, Yali [1 ]
Nakamura, Satoshi [2 ,3 ]
Mitomo, Hideyuki [2 ,4 ]
Yonamine, Yusuke [2 ]
Wang, Guoqing [5 ]
Ijiro, Kuniharu [2 ]
机构
[1] Hokkaido Univ, Grad Sch Life Sci, Kita 10,Nishi 8,Kita Ku, Sapporo 0600810, Japan
[2] Hokkaido Univ, Res Inst Elect Sci, Kita 21,Nishi 10,Kita Ku, Sapporo, Hokkaido 0010021, Japan
[3] Yamagata Univ, Inst Promot Gen Grad Educ IPGE, 4-3-16 Jonan, Yonezawa, Yamagata 9928510, Japan
[4] Tohoku Univ, Inst Multidisciplinary Res Adv Mat, Sendai 9808577, Japan
[5] Ocean Univ China, Inst Evolut & Marine Biodivers, MoE Key Lab Evolut & Marine Biodivers, Qingdao 266003, Peoples R China
基金
日本学术振兴会;
关键词
CHIROPTICAL ACTIVITY; IN-VITRO; SELECTION; NANOPARTICLES; MOLECULES; APTAMER; AMPLIFICATION; BEACONS; SPECTRA; BINDING;
D O I
10.1039/d4cc04017a
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
We report that complexes formed between gold nanorods (AuNRs) and metal-mediated DNA exhibit plasmonic circular dichroism (CD) signals up to similar to 400 times stronger than the molecular CD signal of DNA. This substantial enhancement enables the detection of metal ions, offering a promising approach to analytical applications in chiral biochemistry. Conformational changes in DNA can be observed by the induced plasmonic optical activity from AuNR-DNA complexes, which has afforded the ability to detect metal ions.
引用
收藏
页码:11794 / 11797
页数:4
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