A Robust and Secure Drug Delivery With Single Transmitter and Dual Symmetrical Receivers in an Internet of Bio-Nano Things

被引:0
|
作者
Bulasara, Phani Krishna [1 ]
Sahoo, Somya Ranjan [1 ]
机构
[1] VIT AP Univ, Sch Comp Sci & Engn, Amaravati 522237, India
来源
IEEE INTERNET OF THINGS JOURNAL | 2024年 / 11卷 / 14期
关键词
Drugs; Nanobioscience; Receivers; Molecular communication; Transmitters; Targeted drug delivery; Nanoscale devices; Bio-nano things; capture probability; drug delivery; interarrival time; molecular communication; nanomachine; security; successful transmission; MOLECULAR COMMUNICATION; DESIGN; MODULATION; INTERFACE; DISTANCE; SYSTEM;
D O I
10.1109/JIOT.2024.3393637
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
Bio-nanomachines are designed for targeted drug delivery in the human body. Sometimes the drug is not distributed properly to the intended receiver due to the biochemical reactions and the possible bindings of drug molecules. The blockchain analogy for Bio-Nano has paved new ways for secure drug delivery. The drug molecule is protected with the help of protein cryptography and genetic signature. A protein membrane attached to the drug molecule acts as an encryption key and will be decrypted after matching with the Receiver's unique composition. But, in cellular biology, the protein membrane structures exhibit symmetries. So there is a high chance that the unintended tissues/organs might receive the drug. Hence, the required dosage of the drug will not reach the intended receiver. In our proposal, we are dealing with the appropriate and secure drug delivery for the symmetrical Receivers. A Control Unit monitors the statistics of a Transmitter nanomachine and two Receiver nanomachines to ensure appropriate drug dosage and delivery. We evaluated the Interarrival Time of molecules in a Poisson process following exponential distribution and the Probability of Successful Transmission of molecules. We have also analyzed the possibilities of the malfunctioning of nanomachines. The good working condition of nanomachines improved both the Probability Density Function of the Interarrival Times and the Probability of Successful Transmissions. In our work, we stick to the maximum number of retransmissions as only 1 and achieved a high Probability of Successful Transmissions.
引用
收藏
页码:25074 / 25087
页数:14
相关论文
共 41 条
  • [1] Internet of Nano and Bio-Nano Things: A Review
    Senturk, Seyda
    Kok, Ibrahim
    Senturk, Fatmana
    [J]. SEMANTIC INTELLIGENCE, ISIC 2022, 2023, 964 : 265 - 276
  • [2] Graphene and related materials for the Internet of Bio-Nano Things
    Civas, Meltem
    Kuscu, Murat
    Cetinkaya, Oktay
    Ortlek, Beyza E. E.
    Akan, Ozgur B. B.
    [J]. APL MATERIALS, 2023, 11 (08)
  • [3] The Internet of Bio-Nano Things - Smart Computing in the Human Body
    Fischer, Stefan
    [J]. 2024 IEEE INTERNATIONAL CONFERENCE ON SMART COMPUTING, SMARTCOMP 2024, 2024, : 2 - 2
  • [4] Semi-Autonomous In Vivo Computation in Internet of Bio-Nano Things
    Ali, Muhammad
    Chen, Yifan
    Cree, Michael J.
    [J]. IEEE INTERNET OF THINGS JOURNAL, 2023, 10 (19) : 16845 - 16855
  • [5] Estimation and Detection for Molecular MIMO Communications in the Internet of Bio-Nano Things
    Baydas, O. Tansel
    Cetinkaya, Oktay
    Akan, Ozgur B.
    [J]. IEEE TRANSACTIONS ON MOLECULAR BIOLOGICAL AND MULTI-SCALE COMMUNICATIONS, 2023, 9 (01): : 106 - 110
  • [6] The Internet of Bio-Nano Things in Blood Vessels: System Design and Prototypes
    Lee, Changmin
    Koo, Bon-Hong
    Chae, Chan-Byoung
    Schober, Robert
    [J]. JOURNAL OF COMMUNICATIONS AND NETWORKS, 2023, 25 (02) : 222 - 231
  • [7] Biocyber Interface-Based Privacy for Internet of Bio-nano Things
    El-Fatyany, Aya
    Wang, Hongzhi
    Abd El-atty, Saied M.
    Khan, Mehak
    [J]. WIRELESS PERSONAL COMMUNICATIONS, 2020, 114 (02) : 1465 - 1483
  • [8] Biocyber Interface-Based Privacy for Internet of Bio-nano Things
    Aya El-Fatyany
    Hongzhi Wang
    Saied M. Abd El-atty
    Mehak Khan
    [J]. Wireless Personal Communications, 2020, 114 : 1465 - 1483
  • [9] Population Dynamics of Biosensors for Nano-therapeutic Applications in Internet of Bio-Nano Things
    Misra, Sudip
    Pal, Saswati
    Kaneriya, Shriya
    Tanwar, Sudeep
    Kumar, Neeraj
    Rodrigues, Joel J. P. C.
    [J]. ICC 2020 - 2020 IEEE INTERNATIONAL CONFERENCE ON COMMUNICATIONS (ICC), 2020,
  • [10] Poster: Research Challenges in Implementation of Edge Interfaces for the Internet of Bio-Nano Things
    Okaie, Yutaka
    [J]. PROCEEDINGS OF THE 8TH ACM INTERNATIONAL CONFERENCE ON NANOSCALE COMPUTING AND COMMUNICATION (ACM NANOCOM 2021), 2021,