Genome-wide selection reveals candidate genes associated with multiple teats in Hu sheep

被引：0
|
作者：
Zhou, Wen [1 ]
Zhang, Cheng-long [1 ]
Han, Zhipeng [1 ]
Li, Xiaopeng [1 ]
Bai, Xinyu [1 ]
Wang, Jieru [1 ]
Yang, Ruizhi [1 ]
Liu, Shudong [1 ]
机构：
[1] Tarim Univ, Coll Anim Sci & Technol, Xinjiang, Peoples R China
来源：
ANIMAL BIOTECHNOLOGY | 2024年 / 35卷 / 01期
关键词：
Hu sheep; multiple teats; candidate genes; selection signals; TRAITS; CATTLE; IDENTIFICATION; SIGNATURES; HOLSTEIN; TRANSCRIPTOME; PROTEIN; NUMBER; GROWTH; CELLS;
D O I：
10.1080/10495398.2024.2380766
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
Increasing the number of teats in sheep helps to improve the survival rate of sheep lambs after birth. In order to analyze the candidate genes related to the formation of multiple teats in Hu sheep, the present study was conducted to investigate the genetic pattern of multiple teats in Hu sheep. In this study, based on genome-wide data from 157 Hu sheep, Fst, xp-EHH, Pi and iHS signaling were performed, and the top 5% signal regions of each analyzed result were annotated based on the Oar_v4.0 for sheep. The results show that a total of 142 SNP loci were selected. We found that PTPRG, TMEM117 and LRP1B genes were closely associated with polypodium formation in Hu sheep, in addition, among the candidate genes related to polypodium we found genes such as TMEM117, SLC25A21 and NCKAP5 related to milk traits. The present study screened out candidate genes for the formation of multiple teats at the genomic level in Hu sheep.
引用
收藏
页数：14
相关论文
共 50 条
  • [1] Genome-Wide Selection Signals Reveal Candidate Genes Associated with Plateau Adaptation in Tibetan Sheep
    Song, Yufang
    Yuan, Chao
    An, Xuejiao
    Guo, Tingting
    Zhang, Wentao
    Lu, Zengkui
    Liu, Jianbin
    ANIMALS, 2024, 14 (22):
  • [2] Genetic Diversity, Selection Signatures, and Genome-Wide Association Study Identify Candidate Genes Related to Litter Size in Hu Sheep
    Bao, Jingjing
    Xiong, Jinke
    Huang, Jupeng
    Yang, Peifu
    Shang, Mingyu
    Zhang, Li
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 (17)
  • [3] Genome-wide expression profiling reveals new candidate genes associated with osteoarthritis
    Karlsson, C.
    Dehne, T.
    Lindahl, A.
    Brittberg, M.
    Pruss, A.
    Sittinger, M.
    Ringe, J.
    OSTEOARTHRITIS AND CARTILAGE, 2010, 18 (04) : 581 - 592
  • [4] Genome-wide study for signatures of selection identifies genomic regions and candidate genes associated with milk traits in sheep
    Ebrahimi, Fatemeh
    Gholizadeh, Mohsen
    Sahebalam, Hamid
    MAMMALIAN GENOME, 2025, : 140 - 150
  • [5] Genome-Wide Association Study Reveals Candidate Genes for Litter Size Traits in Pelibuey Sheep
    Hernandez-Montiel, Wilber
    Alberto Martinez-Nunez, Mario
    Porfirio Ramon-Ugalde, Julio
    Ivan Roman-Ponce, Sergio
    Calderon-Chagoya, Rene
    Zamora-Bustillos, Roberto
    ANIMALS, 2020, 10 (03):
  • [6] A genome-wide association study reveals candidate genes for the supernumerary nipple phenotype in sheep (Ovis aries)
    Peng, W. -F.
    Xu, S. -S.
    Ren, X.
    Lv, F. -H.
    Xie, X. -L.
    Zhao, Y. -X.
    Zhang, M.
    Shen, Z. -Q.
    Ren, Y. -L.
    Gao, L.
    Shen, M.
    Kantanen, J.
    Li, M. -H.
    ANIMAL GENETICS, 2017, 48 (05) : 570 - 579
  • [7] Genome-wide search of candidate genes associated with ⟪depth of chest⟫ parameter in Severocavcazskaya sheep breed
    Zuev, Roman, V
    Krivoruchko, Alexander Yu.
    Likhovid, Natalia G.
    VESTNIK TOMSKOGO GOSUDARSTVENNOGO UNIVERSITETA-BIOLOGIYA, 2024, (68):
  • [8] Genome-Wide Methylome Investigation Reveals New Candidate Genes Associated with Arthritis Mutilans.
    Chandran, Vinod
    O'Reilly, Darren
    Haddad, Amir
    Zhang, Yuhua
    Zhai, Guangju
    Codner, Dianne
    Thavaneswaran, Arane
    Rahman, Proton
    Gladman, Dafna L.
    ARTHRITIS & RHEUMATOLOGY, 2014, 66 : S274 - S274
  • [9] Detection of Candidate Genes Associated with Fecundity through Genome-Wide Selection Signatures of Katahdin Ewes
    Sanchez-Ramos, Reyna
    Trujano-Chavez, Mitzilin Zuleica
    Gallegos-Sanchez, Jaime
    Becerril-Perez, Carlos Miguel
    Cadena-Villegas, Said
    Cortez-Romero, Cesar
    ANIMALS, 2023, 13 (02):
  • [10] A genome-wide association study reveals candidate genes and regulatory regions associated with birth weight in pigs
    Deng, Dadong
    Wang, Hongtao
    Han, Kun
    Tang, Zhenshuang
    Li, Xiaoping
    Liu, Xiangdong
    Liu, Xiaolei
    Li, Xinyun
    Yu, Mei
    ANIMAL GENETICS, 2024, 55 (05) : 761 - 765
12345