One Health Approach to Toxoplasmosis: Owner and Dog Seropositivity as Spatial Indicators of Risk Areas for Acquired, Gestational and Congenital Transmission

被引：1

作者：

Sohn-Hausner, Natacha ^{[1
]}

Correa, Ricardo Guedes ^{[2
]}

Kmetiuk, Louise Bach ^{[1
]}

da Silva, Evelyn Cristine ^{[3
]}

de Moraes, Gustavo Nunes ^{[3
]}

Rocha, Gabrielle dos Santos ^{[3
]}

Langoni, Helio ^{[3
]}

Biondo, Alexander Welker ^{[1
,2
]}

机构：

[1] Univ Fed Parana, Grad Coll Cell & Mol Biol, BR-80035050 Curitiba, PR, Brazil

[2] Univ Fed Parana, Grad Coll Vet Med, BR-80035050 Curitiba, PR, Brazil

[3] Sao Paulo State Univ, Dept Vet Hyg & Publ Hlth, BR-18618681 Botucatu, SP, Brazil

来源：

TROPICAL MEDICINE AND INFECTIOUS DISEASE | 2024年 / 9卷 / 07期

关键词：

associated risk ractors; One Health; protozoa; sentinel animals; ticks; zoonoses; CANINE VISCERAL LEISHMANIASIS; PREGNANT-WOMEN; GONDII ANTIBODIES; WATERBORNE TOXOPLASMOSIS; NEOSPORA-CANINUM; IXODES-RICINUS; PARANA STATE; PREVALENCE; INFECTION; DISEASE;

D O I：

10.3390/tropicalmed9070143

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Background: Toxoplasmosis has been of public health concern due to direct associations with socioeconomic vulnerability and inadequate living conditions. Methods: Accordingly, the present study aimed to assess antibodies against T. gondii, historical reported toxoplasmosis cases and associated socio-environmental risk factors in Pinhais, a full urban area of Curitiba, currently the eighth biggest metropolitan area of Brazil. Anti-Toxoplasma gondii antibodies were assessed by an indirect immunofluorescence reaction (RIFI). Owner and dog samples were also tested by IFAT to anti-Leishmania spp. and anti-Trypanosoma cruzi antibodies. Results: Overall, 20/135 (14.8%) persons and 13/133 (9.8%) dogs from 25 different households were considered seropositive to T. gondii. All samples were seronegative to Leishmania spp. and Trypanosoma cruzi. Conclusions: Although no significant covariates were found in the regression model, statistically associated risk factors in the bivariate analysis included no public water use (p = 0.016) and drinking raw milk (p = 0.041) for owners, and obesity (p = 0.028) and tick infestation (p = 0.03) for dogs. In addition, a spatial cluster of T. gondii seropositivity for both owners and their dogs overlapped the location of historic reported cases of human acquired, gestational and congenital toxoplasmosis. Finally, the results herein showed tick infestation as an indicator of socio-environmental risk for T. gondii exposure in the household environment, and dogs may be used as sentinels for human toxoplasmosis cases.

引用

页数：13