Non-invasive Assessment of Intracranial Pressure in Severe Burned Patients: From Animal Models to Bedside

Aims: : Some is known from studies on burn animal models. Burn patients can develop intracranial hypertension. The aim of study is to evaluate feasibility of non-invasive methods for the diagnosis of intracranial hypertension. Methods: : Burns patients were enrolled and studied through ultrasound measurement of optic nerve sheath diameter and transcranial Doppler. Results: : In the 20 patients studied, no pathological values were identified fied without correlations with the extension of the burn. Conclusions: : Starting from animal models, it is legitimate to suspect an underestimation of neuro-complications. The study demonstrates that these methods are applicable to this population, representing an effective method reducing the incidence of neuro-complications.